In patients undergoing catheter ablation for non-reentrant ventricular arrhythmias, the presence of structural heart disease did not significantly affect acute procedural success (89.9% vs 94.3%, p=0.238).
Cohort (n=266)
No
Does catheter ablation of non-reentrant ventricular arrhythmias have comparable acute and long-term success in patients with structural heart disease compared to those without?
Catheter ablation of non-reentrant ventricular arrhythmias is highly effective and safe in patients with structural heart disease, yielding outcomes comparable to those without structural heart disease.
Absolute Event Rate: 89.9% vs 94.3%
p-value: p=0.238
BACKGROUND: Catheter ablation of non-reentrant, commonly termed "idiopathic" ventricular arrhythmias (VA) is highly effective in patients without structural heart disease (SHD). Meanwhile, the outcome of catheter ablation of these arrhythmias in patients with SHD remains unclear. This study sought to characterize the outcome of patients with and without SHD undergoing catheter ablation of non-reentrant VA. METHODS: In this single-centre study the acute and long-term outcome of 266 consecutive patients undergoing catheter ablation of non-reentrant VA was investigated. In 41.0% of patients a SHD was present (n = 109, 80.7% male, age 59.1 ± 14.7 years), 59.0% had no SHD (n = 157; 44.0% male, age 49.9 ± 16.5 years). RESULTS: Acute procedural success (absence of spontaneous or provoked VA at the end of procedure and within 48 h after the procedure) was achieved in 89.9% of patients with SHD vs. 94.3% without SHD (p = 0.238). During a mean follow-up of 34.7 ± 15.1 months a repeat catheter ablation was performed in 19.6% of patients with SHD vs. 13.0% without SHD (p = 0.179). Patients with dilated cardiomyopathy (DCM) were the most likely to require a repeat ablation procedure (32.0% of patients with DCM vs. 13.0% without SHD; p = 0.022). Periprocedural complications occurred in 5.5% of patients with SHD vs. 5.7% without SHD (p > 0.999). All complications were managed without sequelae. CONCLUSIONS: The outcome of catheter ablation of non-reentrant VA in patients with SHD appears good and is comparable to patients without SHD. A slightly higher rate of repeat ablations was observed in patients with DCM.
Schleberger et al. (Tue,) conducted a cohort in Non-reentrant ventricular arrhythmias (n=266). Structural heart disease (SHD) vs. No structural heart disease was evaluated on Acute procedural success (absence of spontaneous or provoked VA at the end of procedure and within 48 h) (p=0.238). In patients undergoing catheter ablation for non-reentrant ventricular arrhythmias, the presence of structural heart disease did not significantly affect acute procedural success (89.9% vs 94.3%, p=0.238).
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