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The boundaries of oral lesions in color images were detected using a live-wire method and compared to expert delineations. Multiple cost terms were analyzed for their inclusion in the final total cost function including color gradient magnitude, color gradient direction, Canny edge detection, and Laplacian zero crossing. The gradient magnitude and direction cost terms were implemented so that they acted directly on the three components of the color image, instead of using a single derived color band. The live-wire program was shown to be considerably more accurate and faster compared to manual segmentations by untrained users.
Chodorowski et al. (Fri,) studied this question.