Infectious Keratitis: A Retrospective Analysis of a Tertiary Care Center

Background/Objectives: Infectious keratitis is a vision-threatening disease. Its prevalence and specific pathogens vary by geographic location. This study characterizes risk profiles, clinical manifestations, and treatment outcomes for various pathogens in the Rostock area. Results: The study included 65 patients (38 viral, 14 bacterial, seven fungal, six parasitic) with a minimum follow-up of three months. The cohort had a mean age of 59 ± 19 years, with 49% female and 51% male participants. All groups showed significant improvement in visual acuity (viral −0.3 logMAR, p = 0.011; parasitic −0.8 logMAR, p = 0.043; fungal −0.9 logMAR, p = 0.018; Wilcoxon). Only the bacterial group did not reach statistical significance (−0.3 logMAR, p = 0.169; Wilcoxon). Final visual acuity did not differ significantly between medical and surgical treatments. Conclusions: No treatment modality (medical vs. surgical) showed superiority regarding visual outcome across pathogen groups. Early diagnosis and prompt therapy initiation are essential to improve visual prognosis and reduce complications.