November 1, 1968

Histone Phosphorylation: Stimulation by Adenosine 3′,5′-Monophosphate

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Abstract

Adenosine cyclic 3',5'-monophosphate at a concentration of 10-(7)M causes a four-to sixfold increase in the rate of histone phosphorylation catalyzed by a liver enzyme preparation. This observation suggests a mechanism for the induction of RNA synthesis by those hormones that cause increases in the concentration of cyclic AMP.

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Thomas A. Langan (Fri,) studied this question.

synapsesocial.com/papers/6a23c23cb7e293e61ca618cb https://doi.org/https://doi.org/10.1126/science.162.3853.579

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Histone Phosphorylation: Stimulation by Adenosine 3′,5′-Monophosphate

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Abstract

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Cite This Study

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Discussion

Journals

Institutions

References and Citations

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