Self-Integrating Bioconductive Myofiber (SIBM): Tissue-Encapsulating Scaffold Where Flesh Wraps Each Fiber for Cardiac Reconstruction

Conventional bioprinting places cells to construct form. This invention proposes the inverse: place one fiber, and living tissue wraps it spontaneously. The Self-Integrating Bioconductive Myofiber (SIBM) is a scaffold fiber designed so that cardiomyocytes, fibroblasts, and vascular endothelial cells adhere and encapsulate each fiber autonomously. Three surface elements drive self-integration: (1) Cell adhesion factor coating — fibronectin, laminin, collagen IV at nanoscale density activates integrin-mediated adhesion; (2) Inductive microcurrent — piezoelectric fiber generates micro-ampere currents that electrophoretically attract cells (same principle as wound healing currents); (3) Nanoscale surface texture — 100-500nm groove structures guide cell alignment via contact guidance, spontaneously reproducing the helical myocardial fiber orientation. Once flesh wraps the fiber, electrical contact is established: fiber electricity drives cell contraction, contraction drives piezoelectric generation — the system becomes self-sustaining the moment of encapsulation. SIBM is the third layer of a three-part invention series: ECCE (what to build, DOI: 10.5281/zenodo.20725907), CPMH (how to build, DOI: 10.5281/zenodo.20725945), SIBM (why it lives). Theoretical basis: V = N / D — when flesh wraps the fiber, external intervention (D) approaches zero and biological density (N) is maximized. The designer places the fiber. The flesh does the rest. Inventor declaration: The inventor does not manufacture this device. Published as open knowledge base for all regenerative medicine researchers, materials scientists, and cardiac surgeons.