Female sex was independently associated with poorer quality of life compared to male sex among Syrian patients admitted with atrial fibrillation (OR 5.2; 95% CI 2.2-7.6; P<0.001).
Cohort (n=406)
No
Does female sex affect quality of life in Syrian patients admitted with atrial fibrillation?
Syrian women admitted with atrial fibrillation experience significantly poorer quality of life compared to men, with female sex and congestive cardiac failure acting as independent predictors of poor QoL.
Odds Ratio: 5.2 (95% CI 2.2–7.6)
p-value: p=<0.001
Background The EuroQoL 5 dimensions is the first validated questionnaire to assess quality of life (QoL) in patients with atrial fibrillation (AF) in Syria. Objective This study aimed to evaluate the gender disparity in QoL in Syrian patients with AF during the ongoing conflict. Methods The study involved patients admitted to the emergency department of Tishreen University Hospital in Latakia, Syria, with AF as the primary diagnosis between June 2023 and June 2024. Arabic versions of the EuroQoL 5 dimensions were administered to patients on admission, and their demographic data were taken from their medical notes. Results A total of 406 satisfied the study criteria, of whom 180 (44%) were males; and the median age was 67 (57- 73) years. Compared with men, women had more congestive cardiac failure (CCF) (32% vs 22%; P =.001) and were more uneducated (48% vs 27%; P <.001). Females demonstrated poorer QoL across all scoring dimensions (activities: 2.4 vs 1.7; mobility: 2.5 vs 1.6; self-care: 2.6 vs 1.8; pain: 2.6 vs 1.7; anxiety: 2.9 vs 1.8; EuroQol Visual Analogue Scale: 49.8 vs 79.8), all of which had P <.001. Multivariable logistic regression demonstrated that women (odds ratio OR: 5.2; 95% confidence interval CI 2.2–7.6; P <.001 and OR 6.2; 95% CI 3.1–9.7; P <.001) and CCF (OR 3.3; 95% CI 1.5–6.9; P <.001 and OR 4.2; 95% CI 2.2–7.3; P <.001) were independently associated with poor QoL. Conclusion Syrian women admitted with AF had poorer QoL than did their men counterparts. CCF and female sex were independent predictors of poor QoL.
Antoun et al. (Thu,) conducted a cohort in Atrial fibrillation (n=406). Female sex vs. Male sex was evaluated on Poor quality of life (OR 5.2, 95% CI 2.2-7.6, p=<0.001). Female sex was independently associated with poorer quality of life compared to male sex among Syrian patients admitted with atrial fibrillation (OR 5.2; 95% CI 2.2-7.6; P<0.001).