We report a general acridine/thiol cooperative photocatalytic system for the metal- and base-free decarboxylative hydrogenation of carboxylic acids under mild conditions. This method accommodates a broad range of substrates with high chemoselectivity and excellent functional group tolerance. Moreover, the system operates efficiently in both batch and continuous flow modes, providing a practical and scalable protocol.
Gao et al. (Wed,) studied this question.
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