Clinical and histopathological effects of topical pentoxifylline on autonomisation processes in rat dorsal randomised skin flaps

Key Points

• The aim is to assess the effects of topical pentoxifylline on the autonomisation of skin flaps in rats.
• Used rat dorsal randomised skin flaps in the study design
• Applied topical pentoxifylline to evaluate its effects
• Conducted histopathological analysis to assess outcomes
• Topical pentoxifylline significantly promoted angiogenesis
• Accelerated the autonomisation of skin flaps was observed
• Potential for reducing complications in reconstructive surgery was identified

Abstract