August 18, 2022Open Access

Modeling non-linear relationships in epidemiological data: The application and interpretation of spline models

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Abstract

Spline functions should be considered more often as they are flexible and can be applied in commonly used regression analysis. RCS regression is generally recommended for prediction research (i.e., to obtain the predicted outcome for a specific exposure value), whereas LSP regression is recommended if one is interested in the effects in a population.

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Authors

Noah A. Schuster

University of Iowa

Judith J. M. Rijnhart

University of South Florida

Jos W. R. Twisk

Cardiac Imaging

Journals

Frontiers in Epidemiology

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Institutions

Vrije Universiteit Amsterdam

Amsterdam University Medical Centers

GGD Amsterdam

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Schuster et al. (Thu,) studied this question.

synapsesocial.com/papers/69da25f0b48bb130d46845a9 — DOI: https://doi.org/10.3389/fepid.2022.975380

Also consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

Nonlinearity in the Epidemiology of Complex Health and Disease Processes· 1998 · 109 citations
An Introduction to Statistical Learning· 2013 · 11,624 citations
Analysis of Health Surveys· 1999 · 1,045 citations
Splines as a Useful and Convenient Statistical Tool· 1979 · 255 citations
Explaining Variability of Cost Using a Severity-of-lllness Measure for ICU Patients· 1990 · 82 citations

Also consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

Nonlinearity in the Epidemiology of Complex Health and Disease Processes· 1998 · 109 citations
An Introduction to Statistical Learning· 2013 · 11,624 citations
Analysis of Health Surveys· 1999 · 1,045 citations
Splines as a Useful and Convenient Statistical Tool· 1979 · 255 citations
Explaining Variability of Cost Using a Severity-of-lllness Measure for ICU Patients· 1990 · 82 citations

Modeling non-linear relationships in epidemiological data: The application and interpretation of spline models

Key Points

Abstract

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Connected Papers

Discussion

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

Connected Papers

Discussion

Cite this study

Also consider

Also consider