July 13, 2024Open Access

Sanguinarine Induces Necroptosis of HCC by Targeting PKM2 Mediated Energy Metabolism

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Abstract

Abnormal metabolism is the hallmark of hepatocellular carcinoma. Targeting energy metabolism has become the major focus of cancer therapy. The natural product, sanguinarine, displays remarkable anti-tumor properties by disturbing energy homeostasis; however, the underlying mechanism has not yet been elucidated.

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Kong et al. (Sat,) studied this question.

synapsesocial.com/papers/68e6066db6db64358759a4df — DOI: https://doi.org/10.3390/cancers16142533

Authors

Rui Kong

Army Medical University

Nan Wang

Xihua University

Chunli Zhou

Qingdao University

Journals

Cancers

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Institutions

Shanghai Jiao Tong University

Tongji University

Nanjing Medical University

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Sanguinarine Induces Necroptosis of HCC by Targeting PKM2 Mediated Energy Metabolism

Key Points

Abstract

Citation Network

Connected Papers

Discussion

Cite this study

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

Connected Papers

Discussion