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Patients who have many seizures before therapy or who have an inadequate response to initial treatment with antiepileptic drugs are likely to have refractory epilepsy.
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Kwan et al. (Thu,) studied this question.
www.synapsesocial.com/papers/69d56e2e75589c71d767d49f — DOI: https://doi.org/10.1056/nejm200002033420503
Patrick Kwan
Martin J. Brodie
New England Journal of Medicine
Western Infirmary
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