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Brief Reports1 May 1992Intracerebral Bacillary Angiomatosis in a Patient Infected with Human Immunodeficiency VirusDavid H. Spach, MD, Lori A. Panther, MD, David R. Thorning, MD, Jeffrey E. Dunn, MD, James J. Plorde, MD, Richard A. Miller, MDDavid H. Spach, MDSearch for more papers by this author, Lori A. Panther, MDSearch for more papers by this author, David R. Thorning, MDSearch for more papers by this author, Jeffrey E. Dunn, MDSearch for more papers by this author, James J. Plorde, MDSearch for more papers by this author, Richard A. Miller, MDSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-116-9-740 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptBacillary angiomatosis is a recently described illness that results from infection with a novel, rickettsia-like, gram-negative bacillus (1, 2). This disorder occurs predominantly in patients infected with human immunodeficiency virus (HIV) and typically manifests as angiomatous cutaneous lesions (3, 4), although dissemination (5) and peliosis hepatis (6) can occur. According to our review of the literature and MEDLINE search, the spectrum of bacillary angiomatosis has not included intracranial mass lesions. We report a case of a patient with bacillary angiomatosis who had cutaneous and central nervous system involvement and describe the patient's response to erythromycin therapy.Case ReportA 49-year-old...References1. Relman D, Loutit J, Schmidt T, Falkow S, and Tompkins L. The agent of bacillary angiomatosis. An approach to the identification of uncultured pathogens. N Engl J Med. 1990;323:1573-80. CrossrefMedlineGoogle Scholar2. Birtles R, Harrison T, and Taylor A. The causative agent of bacillary angiomatosis Letter. N Engl J Med. 1991;325:1447-8. CrossrefMedlineGoogle Scholar3. Cockerell C and LeBoit P. Bacillary angiomatosis: a newly characterized, pseudoneoplastic, infectious, cutaneous vascular disorder. J Am Acad Dermatol. 1990;22:501-12. CrossrefMedlineGoogle Scholar4. Spach D. Bacillary angiomatosis. Int J Dermatol. 1992;31:19-24. CrossrefMedlineGoogle Scholar5. Milam M, Balerdi M, Toney J, Foulis P, Milam C, and Behnke R. Epithelioid angiomatosis secondary to disseminated cat scratch disease involving the bone marrow and skin in a patient with acquired immune deficiency syndrome: a case report. Am J Med. 1990;88:180-3. CrossrefMedlineGoogle Scholar6. Perkocha L, Geaghan S, Yen T, Nishimura S, Chan S, and Garcia-Kennedy R. Clinical and pathological features of bacillary peliosis hepatis in association with human immunodeficiency virus infection. N Engl J Med. 1990;323:1581-6. CrossrefMedlineGoogle Scholar7. Berger T, Tappero J, Kaymen A, and LeBoit P. Bacillary (epithelioid) angiomatosis and concurrent Kaposi's sarcoma in acquired immunodeficiency syndrome. Arch Dermatol. 1989;125:1543-7. CrossrefMedlineGoogle Scholar8. LeBoit P. The expanding spectrum of a new disease, bacillary angiomatosis. Arch Dermatol. 1990;126:808-11. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: David H. Spach, MD; Lori A. Panther, MD; David R. Thorning, MD; Jeffrey E. Dunn, MD; James J. Plorde, MD; Richard A. Miller, MDFrom the University of Washington Medical Center and the Seattle Department of Veterans Affairs Medical Center, Seattle, Washington. For current author addresses, see end of text. 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Spach et al. (Fri,) studied this question.