July 12, 2005

Enhanced Tumorocidal Effect of Chemotherapy With Preoperative Radiotherapy for Rectal Cancer: Preliminary Results—EORTC 22921

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Abstract

In patients with rectal cancer, preliminary results of EORTC Trial 22921 indicate that the addition of CT to preop RT induces down-sizing, downstaging, and significant changes in histologic characteristics. Longer follow-up is needed to assess the impact on local control and survival.

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Authors

Jean-François Bosset

G. Calais

Laurent Mineur

Journals

Journal of Clinical Oncology

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Institutions

Centre Hospitalier Universitaire de Tours

European Organisation for Research and Treatment of Cancer

Centre Hospitalier Universitaire de Poitiers

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Enhanced Tumorocidal Effect of Chemotherapy With Preoperative Radiotherapy for Rectal Cancer: Preliminary Results—EORTC 22921

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Abstract

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Discussion

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