Does cumulative exposure to cardiovascular risk factors from early to middle adulthood worsen cognitive function in midlife?
Adults from early to middle adulthood
Cumulative exposure to cardiovascular risk factors (CVRFs)
Exposure within recommended guidelines
Cognitive function in midlife
Cumulative exposure to cardiovascular risk factors from early to middle adulthood is associated with worse cognitive function in midlife.
Cumulative exposure to CVRFs from early to middle adulthood, especially above recommended guidelines, was associated with worse cognition in midlife. The meaning of this association and whether it warrants more aggressive treatment of CVRFs earlier in life require further investigation.
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Kristine Yaffe
Eric Vittinghoff
Mark J. Pletcher
Circulation
National Institute on Aging
Kaiser Permanente
San Francisco VA Medical Center
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Yaffe et al. (Tue,) studied this question.
www.synapsesocial.com/papers/69d5722575589c71d767e535 — DOI: https://doi.org/10.1161/circulationaha.113.004798
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