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THE two plasma forms of apolipoprotein B—B-100 and B-48 — are important proteins in mammalian lipoprotein metabolism.1 Both are products of the same structural gene,2 which in humans is located on chromosome 2.3 4 5 Apolipoprotein B-100 is a glycoprotein containing 4536 amino acids;6 7 8 9 10 and it is synthesized by the liver.1 It is an important structural protein in very-low-density lipoproteins (VLDL), which are rich in triglycerides, and low-density lipoproteins (LDL), which are rich in cholesteryl esters. Apolipoprotein B-100 is virtually the only protein component of human LDL, and it is the ligand responsible for the recognition and uptake of LDL by cellular . . .
Young et al. (Thu,) studied this question.
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