Does a fixed dose of dabigatran provide similar efficacy and safety compared to warfarin in the treatment of acute venous thromboembolism?
Patients with acute venous thromboembolism
Fixed dose of dabigatran
Warfarin
A fixed dose of dabigatran is as effective and safe as warfarin for treating acute venous thromboembolism, with the added benefit of not requiring laboratory monitoring.
For the treatment of acute venous thromboembolism, a fixed dose of dabigatran is as effective as warfarin, has a safety profile that is similar to that of warfarin, and does not require laboratory monitoring. (ClinicalTrials.gov number, NCT00291330.)
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Sam Schulman
Clive Kearon
Ajay K. Kakkar
New England Journal of Medicine
Harvard University
Brigham and Women's Hospital
McMaster University
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Schulman et al. (Sun,) studied this question.
www.synapsesocial.com/papers/69d56c1675589c71d767cb6e — DOI: https://doi.org/10.1056/nejmoa0906598
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