Age ≥85 years was not an independent predictor of in-hospital mortality following PCI (OR 1.22; 95% CI 0.37-4.07), despite a higher unadjusted mortality rate of 2.5%.
Cohort (n=10,847)
Yes
Does percutaneous coronary intervention in very elderly patients (≥ 85 years) result in acceptable in-hospital outcomes compared to younger patients?
Advanced age (≥ 85 years) is not an independent predictor of in-hospital mortality following PCI, suggesting that very elderly patients should not be denied intervention based on age alone.
Effect estimate: OR 1.22 (95% CI 0.37-4.07)
p-value: p=<0.001
Coronary heart disease is the leading cause of death among the elderly (> 65 years) and the very elderly (> 85 years). Little information is available regarding the outcome of very elderly patients referred for PCI in the current era of improved techniques, devices, and pharmacotherapy. The objective of the current study was to evaluate the clinical characteristics and outcomes of very elderly patients > or = 85 years of age in a large, contemporary, multi-institutional PCI database. Five hospitals in the New York City metropolitan area contributed these prospectively defined data elements on consecutive patients undergoing PCI from 1 January 1998 to 1 October 1999. Of 10,847 patients, 5,341 (49%) were younger than 65 years, 3,342 (31%) were 65-74 years, 1,885 (17%) were 75-84 years, and 279 (2.6%) were at least 85 years of age. Following PCI, the very elderly developed stroke (P or = 85 years was not an independent predictor of in-hospital mortality (OR = 1.22; 95% CI = 0.37-4.07). The very elderly should not be refused PCI on the basis of advanced age alone.
Dynina et al. (Wed,) conducted a cohort in Coronary heart disease (n=10,847). Percutaneous coronary intervention vs. Younger patients was evaluated on In-hospital mortality (OR 1.22, 95% CI 0.37-4.07, p=<0.001). Age ≥85 years was not an independent predictor of in-hospital mortality following PCI (OR 1.22; 95% CI 0.37-4.07), despite a higher unadjusted mortality rate of 2.5%.