Is fenfluramine-phentermine therapy associated with valvular heart disease?
Patients receiving fenfluramine-phentermine therapy
Fenfluramine-phentermine therapy
Valvular heart diseasesafety
Fenfluramine-phentermine therapy raises significant safety concerns regarding the development of valvular heart disease and pulmonary hypertension.
These cases arouse concern that fenfluramine-phentermine therapy may be associated with valvular heart disease. Candidates for fenfluramine-phentermine therapy should be informed about serious potential adverse effects, including pulmonary hypertension and valvular heart disease.
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Heidi M. Connolly
Jack L. Crary
Michael D. McGoon
New England Journal of Medicine
Mayo Clinic
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Connolly et al. (Thu,) studied this question.
www.synapsesocial.com/papers/69d6c9bd733a2b54c8aa837b — DOI: https://doi.org/10.1056/nejm199708283370901