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Profilactin and profilin have been purified from calf thymus and calf brain. Thymus profilactin could be crystallized with a similar technique as described earlier for the spleen protein. 2. Preparations of profilactin from the three calf tissues spleen, thymus and brain contain a mixture of beta actin and gamma actin. The ratio beta/gamma differs between the tissues, but is constant throughout the purification steps. 3. The properties of profilin isolated from three sources (spleen, thymus and brain) indicate that it is a highly conserved protein.
Blikstad et al. (Tue,) studied this question.