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ACT with a nonmyeloablative preparative regimen using either TIL- or TCR gene-transduced cells and interleukin-2 can mediate complete and durable regression of melanoma brain metastases. This strategy can be used safely in selected patients with metastatic melanoma to the brain.
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Jenny J. Hong
Steven A. Rosenberg
Mark E. Dudley
Clinical Cancer Research
National Cancer Institute
National Institutes of Health Clinical Center
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Hong et al. (Thu,) studied this question.
www.synapsesocial.com/papers/69e68f2156489ac743ff1b9a — DOI: https://doi.org/10.1158/1078-0432.ccr-10-1507