September 1, 1994

Arm muscle sympathetic nerve activity during preparation for and initiation of leg-cycling exercise in humans

Structured PICO

Does leg-cycling exercise reduce arm muscle sympathetic nerve activity in healthy young subjects?

Population

11 healthy young subjects

Intervention

1 min of leg-cycling exercise at one or more submaximal workloads (range 33-266 W; approximately 10-80% of peak power output)

Comparator

Upright seated rest (control)

Outcome

Muscle sympathetic nerve activity (MSNA) from the radial nerve in the armsurrogate

Sympathetic vasoconstrictor nerve activity to nonactive skeletal muscle decreases immediately before and remains suppressed during the initiation of upright dynamic exercise.

Abstract

We tested the hypothesis that sympathetic vasoconstrictor nerve activity to nonactive skeletal muscle (MSNA) decreases immediately before and remains suppressed during initiation of conventional large muscle upright dynamic exercise in humans. In 11 healthy young subjects, adequate recordings of MSNA from the radial nerve in the arm were obtained during upright seated rest (control) and throughout 1 min of leg-cycling exercise at one or more submaximal workloads (range 33-266 W; approximately 10-80% of peak power output). MSNA was analyzed during four consecutive time intervals; control, preparation for cycling (end of control to onset of pedal movement), initiation of cycling (onset of pedal movement to attainment of target power output), and the initial 60 s of cycling at target power output. MSNA decreased (P or = 60% of peak power output.(ABSTRACT TRUNCATED AT 250 WORDS)

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