A review of current literature outlines the embryology, genetics, and diagnostic approach for left ventricular noncompaction and proposes a management strategy for this rare genetic cardiomyopathy.
This review summarizes the embryology, genetics, diagnosis, and management of left ventricular noncompaction cardiomyopathy.
Isolated left ventricular noncompaction (LVNC) is a genetic cardiomyopathy characterized by prominent ventricular trabeculations and deep intertrabecular recesses, or sinusoids, in communication with the left ventricular cavity. The low prevalence of patients with this cardiomyopathy presents a unique challenge for large, prospective trials to assess its pathogenesis, management, and outcomes. In this paper we review the embryology and genetics of LVNC, the diagnostic approach, and propose a management approach based on the current literature available.
Bennett et al. (Fri,) conducted a review in Left ventricular noncompaction (LVNC). A review of current literature outlines the embryology, genetics, and diagnostic approach for left ventricular noncompaction and proposes a management strategy for this rare genetic cardiomyopathy.
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