Does the Wang-Zwische dual lumen cannula reduce recirculation compared to femoro-jugular and femoro-femoral configurations in a mock VV-ECMO circuit?
In a mock VV-ECMO circuit, the Wang-Zwische dual lumen cannula significantly reduced recirculation compared to traditional femoro-jugular and femoro-femoral cannulation strategies.
A limitation of veno-venous extracorporeal membrane oxygenation (VV-ECMO) is the recirculating of newly oxygenated blood back to the VV-ECMO circuit. We compared cannulation strategies for combating recirculation utilizing a mock circulation loop (MCL) with ultrasonic flow probes and pressure transducers ensuring that the MCL was run at physiological hemodynamic parameters. Mean recirculation percentages were lower (ANOVA, F = 14.25; p = 0.0001) with the Wang-Zwische dual lumen cannula (4.00 ± 1.77, n = 7) than both the femoro-jugular (15.23 ± 7.00, n = 8) and the femoro-femoral cannulation configurations (13.49 ± 1.44, n = 8).
Jayewardene et al. (Sun,) studied this question.