Key points are not available for this paper at this time.
Oxidative stress is a phenomenon caused by an imbalance between production and accumulation of oxygen reactive species (ROS) in cells and tissues and the ability of a biological system to detoxify these reactive products. ROS can play, and in fact they do it, several physiological roles (i.e., cell signaling), and they are normally generated as by-products of oxygen metabolism; despite this, environmental stressors (i.e., UV, ionizing radiations, pollutants, and heavy metals) and xenobiotics (i.e., antiblastic drugs) contribute to greatly increase ROS production, therefore causing the imbalance that leads to cell and tissue damage (oxidative stress). Several antioxidants have been exploited in recent years for their actual or supposed beneficial effect against oxidative stress, such as vitamin E, flavonoids, and polyphenols. While we tend to describe oxidative stress just as harmful for human body, it is true as well that it is exploited as a therapeutic approach to treat clinical conditions such as cancer, with a certain degree of clinical success. In this review, we will describe the most recent findings in the oxidative stress field, highlighting both its bad and good sides for human health.
Building similarity graph...
Analyzing shared references across papers
Loading...
Gabriele Pizzino
Natasha Irrera
Mariapaola Cucinotta
Oxidative Medicine and Cellular Longevity
SHILAP Revista de lepidopterología
University of Messina
Morpho (United States)
Building similarity graph...
Analyzing shared references across papers
Loading...
Pizzino et al. (Sun,) studied this question.
www.synapsesocial.com/papers/69d6876d2c8f994bcf1f2e69 — DOI: https://doi.org/10.1155/2017/8416763