Higher daily step counts were associated with lower NYHA class and better physical and HF-specific quality of life, but not mood symptoms or LVEF, in patients with HF and depression.
Cross-Sectional (n=222)
Is objectively measured daily step count associated with mood, HRQoL, and clinical characteristics in recently hospitalized patients with systolic HF and comorbid depression?
In recently hospitalized patients with systolic HF and depression, physical activity is very low (median 1170 steps/day), and higher step counts correlate with better physical and HF-specific quality of life but not mood or LVEF.
OBJECTIVE: Physical activity (PA) can improve symptoms of both depression and heart failure (HF), but objective activity data among recently hospitalized HF patients with comorbid depression are lacking. We examined PA and the relationship between daily step counts and mood, health-related quality of life (HRQoL), and heart health among patients enrolled in a clinical trial treating HF and comorbid depression. METHODS: We screened hospitalized patients with systolic HF (left ventricular ejection fraction LVEF ≤45%) and New York Heart Association class II-IV symptoms for depression using the two-item Patient Health Questionnaire (PHQ-2) and telephoned screen-positive patients to administer the PHQ-9 2 weeks after discharge. If the patient scored PHQ-9 ≥10 and agreed to continue in our study, we administered our baseline assessment and mailed them an armband accelerometer. We instructed patients to wear the armbands for 7 days before returning them and classified their data as "usable" if they wore it ≥10 hours per day on ≥4 separate days. RESULTS: We mailed accelerometers to 531 depressed HF patients, and 222 (42%) returned them with usable data. Their median age was 64 years, 54% were women, 23% were non-White, and they walked a median of 1170 steps daily. Higher median daily step counts were associated with lower New York Heart Association class and better physical- and HF-specific HRQoL, but not mood symptoms, mental HRQoL, or LVEF. CONCLUSIONS: Patients with HF and comorbid depression are generally sedentary after hospital discharge. Although mood symptoms and LVEF were unrelated to objective PA, patients with higher step counts self-reported better HRQoL.Trial Registration:ClinicalTrials.gov identifier NCT02044211.
Holber et al. (Mon,) conducted a cross-sectional in Systolic Heart Failure and Comorbid Depression (n=222). Daily step count was evaluated on Relationship between daily step counts and mood, health-related quality of life, and heart health. Higher daily step counts were associated with lower NYHA class and better physical and HF-specific quality of life, but not mood symptoms or LVEF, in patients with HF and depression.
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