Does initial treatment with catheter cryoballoon ablation reduce the incidence of persistent atrial fibrillation or recurrent atrial tachyarrhythmia in patients with paroxysmal atrial fibrillation compared to antiarrhythmic drugs?
Patients with paroxysmal atrial fibrillation
Initial treatment with catheter cryoballoon ablation
Initial use of antiarrhythmic drugs
Incidence of persistent atrial fibrillation or recurrent atrial tachyarrhythmia over 3 years of follow-upcomposite
Initial treatment with catheter cryoballoon ablation reduces the progression of paroxysmal atrial fibrillation compared to antiarrhythmic drugs over a 3-year period.
Initial treatment of paroxysmal atrial fibrillation with catheter cryoballoon ablation was associated with a lower incidence of persistent atrial fibrillation or recurrent atrial tachyarrhythmia over 3 years of follow-up than initial use of antiarrhythmic drugs. (Funded by the Cardiac Arrhythmia Network of Canada and others; EARLY-AF ClinicalTrials.gov number, NCT02825979.).
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Jason G. Andrade
Electrophysiology
Marc W. Deyell
Electrophysiology
Laurent Macle
Electrophysiology
New England Journal of Medicine
University of Toronto
University of British Columbia
McMaster University
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Andrade et al. (Mon,) studied this question.
synapsesocial.com/papers/69cdb9be038a83c39e428d17 — DOI: https://doi.org/10.1056/nejmoa2212540