Perceval sutureless aortic valve replacement resulted in postoperative thrombocytopenia in 66.1% of patients, though it was not associated with significant adverse clinical outcomes.
Observational (n=121)
No
Is Perceval sutureless aortic valve replacement safe and what is its effect on postoperative platelet counts in Asian patients with aortic stenosis?
Perceval sutureless AVR is safe and effective in Asian patients but is associated with postoperative thrombocytopenia, suggesting it should be avoided in patients at high bleeding risk.
BACKGROUND: This study analyzed the safety and performance of the Perceval valve for aortic valve replacement (AVR) in patients at 1 year after undergoing aortic stenosis (AS) treatment, and its effect on significant declines in the platelet count during the immediate postoperative period. METHODS AND RESULTS: /μL), and a sternotomy approach as significant risk factors for postoperative thrombocytopenia. One (0.8%) patient died within 30 days after the procedure. The 2-year site-reported event rate was 14% (n=17) for all-cause mortality, 0.8% (n=1) for cardiac mortality, 4.1% (n=5) for stroke, and 1.7% (n=2) for endocarditis and valve-related reoperation; there were no instances of paravalvular leakage or structural valve deterioration. CONCLUSIONS: Thrombocytopenia was common after Perceval sutureless AVR, although its impact was not significant. Although Perceval sutureless AVR was found to be a safe and effective option, preoperative assessment of potential bleeding should be performed and the Perceval valve should not be used for patients with a high bleeding risk.
Nakayama et al. (Fri,) conducted a observational in Aortic valve stenosis (n=121). Perceval sutureless aortic valve replacement was evaluated on Incidence of postoperative thrombocytopenia (platelet count <50×10³/μL). Perceval sutureless aortic valve replacement resulted in postoperative thrombocytopenia in 66.1% of patients, though it was not associated with significant adverse clinical outcomes.