Is Type 2 diabetes associated with lower cognitive performance?
Type 2 diabetes is associated with cognitive decline, highlighting the need for high-quality, standardized meta-analyses to better understand this relationship across different cognitive domains.
Type 2 diabetes appears to be associated with lower cognitive performance in several cognitive domains and in different age groups. However, high-quality meta-analyses on the subject are still needed. Future reviews must follow the PRISMA guidelines and take into account the risk of bias of the original studies through sensitivity analyses and the heterogeneity of the studies by conducting subgroup analyses for example according to age group and disease duration. The meta-analyses that aim to study the entire type 2 diabetes population without excluding severe comorbidities, should assess concept formation and reasoning, construction and motor performance, perception, and verbal functions and language skills in addition to the cognitive domains that have been most frequently analysed in the reviews conducted so far.
Sola et al. (Mon,) studied this question.
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