Current Update on Electrospun Nanofiber Mats as a Wound Healing Drug Carrier

Electrospun nanofiber mats are being researched as attractive wound-healing drug carriers owing to their exclusive features, large active surface area, interlinked porosity, and customizable drug release kinetics. These mats may be infused with antibiotics, growth hormones, or stem cells to hasten the process of healing and lessen the likelihood of problems. Controlled and sustained medication delivery is the key payback of electrospun nanofiber mats. Electrospun nanofiber mats promote wound healing in part because of the favorable milieu they provide cell adhesion and proliferation of the affected tissue due to their enhanced active surface area. Mats of many kinds are discussed in the review. Electrospun nanofiber membranes can be created in a diversity of configurations, along with a single layer, a coaxial structure, and many layers. Recent studies have shown the efficacy of using electrospun nanofiber mats to deliver a variety of therapeutic compounds for wound healing. Treatment of wound infections using antibiotic-loaded electrospun nanofiber mats may help slow the spread of antibiotic-resistant bacteria. Electrospun nanofiber mats supplemented with growth hormones are known to hasten wound healing by encouraging the local tissue’s proliferation and differentiation. Delivery of stem cells to the wound site, where they may develop into new skin cells and stimulate tissue regeneration, can be accomplished with the help of electrospun nanofiber mats. In conclusion, electrospun nanofiber mats provide an exciting new platform for the delivery of drugs to promote wound healing. Their enormous surface area, interconnected porosity, and adaptable drug release kinetics all make them excellent vehicles for delivering a wide range of therapeutic medicines to the wound site.