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Purpose: To perform a comparative analysis of diagnostic efficiency of PET/CT with 68 Ga-DOTA-TATE and 68 Ga-FAPI on the example of clinical cases of NEO (detection of primary tumor and extra-organ metastases). Material and methods: Two patients with pancreatic NEO underwent PET/CT studies with 68 Ga-DOTA-TATE and 68 Ga-FAPI before treatment. PET/CT with 68 Ga-DOTA-TATE successfully visualized primary tumors in both patients; evidence of a metastatic process in the liver was obtained in one patient. PET/CT with 68 Ga-FAPI showed non-optimal visualization of primary tumors, no liver metastases were detected. Conclusion: PET/CT with 68 Ga-DOTA-TATE is a more effective method of radionuclide diagnostics of NEO than PET/CT with 68 Ga-FAPI.
Belkin et al. (Thu,) studied this question.
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