Wound dressings prevent complications such as infections and potentially severe outcomes, including death, if wounds are left untreated. Wound dressings have evolved from rudimentary coverings made from natural materials to sophisticated, functionalized dressings designed to enhance wound healing and support tissue repair more effectively. These materials are often referred to as scaffolds in the literature, with wound dressing scaffolds intended to interact with native skin tissue and support tissue regeneration, whereas conventional wound dressings are designed primarily to protect the wound without directly interacting with the underlying tissue. However, there is a functional overlap between these categories, and the boundary is often blurred due to the increasing multifunctionality of modern wound dressings. This review will focus on developing wound dressings (scaffolds or not) based on fibers, their properties, and applications. Advances in nanomedicine have highlighted significant improvements in wound care by applying electrospun nanofibers that mimic the natural extracellular matrix. Therefore, this review explores recent advances in wound healing physiology, highlights nanofiber-based wound dressing materials developed through electrospinning, and distinguishes conventional dressings from multifunctional wound dressing scaffolds.
Fard et al. (Thu,) studied this question.