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This is a Literature Review study.

September 5, 2025

Considerations for hormone therapy use in survivors of breast cancer

Key Points

The use of hormone therapy presents complex health implications for breast cancer survivors, requiring careful consideration.
Guidelines have historically recommended against hormone therapy, highlighting ongoing debates about its safety and efficacy.
Long-term oncologic data remain insufficient, leading to uncertainty regarding recommendations for breast cancer survivors.
Quality-of-life concerns for survivors are significant, yet definitive data to guide treatment decisions are currently lacking.

Abstract

The use of hormone therapy in survivors of breast cancer is complex and contentious. Historically, guidelines have strongly advised against using hormone therapy. Its safety likely depends on many factors. However, long-term oncologic data are lacking, leaving women with unresolved quality-of-life and health concerns and practitioners uncertain about their recommendations. In the short term, there will not be definitive data, and decisions must be made based on the existing imperfect evidence.

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Cite this study

Holly J. Pederson (Tue,) studied this question.

www.synapsesocial.com/papers/68bb5f266d6d5674bcd0314b — DOI: https://doi.org/10.1097/gme.0000000000002629

Authors

Holly J. Pederson

Journals

Menopause The Journal of The North American Menopause Society

Actions

Institutions

Cleveland Clinic

References and Citations

Connected Papers

Building similarity graph...

Analyzing shared references across papers

Considerations for hormone therapy use in survivors of breast cancer

Key Points

Abstract

Citation Network

Connected Papers

Discussion

Cite this study

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

Connected Papers

Discussion

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