The clinical treatment of different toxicities is the focus of Agada Tantra, a subspecialty of Ashtanga Ayurveda (Visha). The Sushruta Samhita (Kalpa Sthana) describes a highly effective class of anti-toxic medications called Ekasara Gana, which are specifically recommended for systemic toxicities such as Sarpadashta Visha (snakebite envenomation). This group includes one mineral component (Krishna Mruttika, also known as black earth) and eighteen medicinal herbs. The botanical identity, chemical composition, and contemporary pharmacological effects of the Ekasara Gana dravyas are examined in this review article. The study supports the traditional Vishaghna (anti-toxic) claims by examining recent research, showing that a sizable portion of these herbs have potent hepatoprotective (72.22%), anti-inflammatory (83.33%), and antioxidant qualities, making them extremely pertinent for contemporary integrative toxicology.
Dr. Gajendra Singh*1, Dr. Hemlata Dixit2, Dr. Archana Sharma3 (Fri,) studied this question.