Technical, environmental, and economic assessment of anaerobic digestion of pre-treated municipal organic waste for energy production and reuse of liquid digestate

• Physical and enzymatic pre-treatments of OFMSW increased biogas and methane yields. • Hydrodynamic cavitation allowed greater scalability of AD at the pilot scale. • Digestate liquid fraction was as efficient as mineral control in L. sativum growth. • LCA highlighted nutrient addition to digestate as the main environmental hotspot. • Economic analysis identified the physical pre-treatment as the most cost-effective.