ASBMB Learning Objectives (https://www.asbmb.org/education/core-concept-teaching-strategies/foundational-concepts/structure-function) 2. Structure is determined by several factors Students should be able to recognize the repeating units in biological macromolecules and be able to discuss the structural impacts of the covalent and noncovalent interactions involved (Introductory). Students should be able to discuss the chemical and physical relationships between composition and structure of macromolecules (Introductory).
Pettit et al. (Tue,) studied this question.