ASBMB Learning Objectives (https://www.asbmb.org/education/core-concept-teaching-strategies/foundational-concepts/structure-function) 2. Structure is determined by several factors Students should be able to recognize the repeating units in biological macromolecules and be able to discuss the structural impacts of the covalent and noncovalent interactions involved (Introductory). Students should be able to compare and contrast the primary, secondary, tertiary and quaternary structures of proteins (Intermediate). Students should be able to use various bioinformatics approaches to analyze macromolecular primary sequence and structure (Intermediate). 4. Macromolecular interactions Students should be able to discuss the impact of specificity or affinity changes on biological function and any potential evolutionary impact (Introductory). Students should be able to discuss the interactions between a variety of biological molecules (including proteins, nucleic acids, lipids, carbohydrates and small organics, etc.) and describe how these interactions impact specificity or affinity leading to changes in biological function (Intermediate). 6. The biological activity of macromolecules is often regulated Students should be able to compare and contrast various mechanisms for regulating the function of a macromolecule or an enzymatic reaction or pathway (Introductory). Students should be able to discuss the advantages and disadvantages of regulating a reaction allosterically (Intermediate). Students should be able to discuss examples of allosteric regulation, covalent regulation and gene level alterations of macromolecular structure-function (Intermediate).
Shuchismita Dutta (Sun,) studied this question.