BPC-157

Also known as: Body Protection Compound 157, pentadecapeptide BPC-157

Preclinical and limited clinical literature on BPC-157, a synthetic pentadecapeptide studied in wound healing and GI models.

BPC-157 research graphical abstract
Research landscape graphic for BPC-157; Synapse pages are informational and not medical advice.

What does the research say about BPC-157?

BPC-157 appears primarily in rodent wound-healing, tendon, and GI injury models. Human evidence remains sparse; Synapse surfaces indexed papers and active investigators for transparent literature review.

Synapse surfaces peer-reviewed research and researcher networks for informational purposes only. This page does not provide medical advice, dosing guidance, or treatment recommendations.

Research feed: BPC-157

11 indexed papers matched to curated MeSH concepts in the last 90 days.

12w ago
Top Journal
Level 5: Review

Stable Gastric Pentadecapeptide BPC 157 as a Therapy of SevereElectrolyte Disturbances in Rats

Implication

This review explores BPC 157's effectiveness in managing electrolyte imbalances in rats, highlighting its therapeutic potential.

Current Neuropharmacology
University of Zagreb
1w agoOpen Access
Level 5

BPC-157 and Its Novel Hybrid Analogs as Inhibitors of Acetylcholinesterase

Implication

Randomized trial investigates BPC-157 and its analogs' inhibitory effects on acetylcholinesterase, indicating potential for neurodegenerative therapies.

International Journal of Molecular Sciences
Medical University of Warsaw
11w agoOpen Access
Level 5

From Regeneration to Analgesia: The Role of BPC-157 in Tissue Repair and Pain Management

Implication

Preclinical research explores BPC-157's effects on tissue healing and pain relief, indicating therapeutic promise.

International Journal of Molecular Sciences
Johns Hopkins University
1w agoOpen Access
Level 5

Unilateral Adrenalectomy, and the Stable Pentadecapeptide BPC 157 as Therapy in Rats—A Cytoprotection Approach

Implication

Randomized trial investigates BPC 157's cytoprotective effects post adrenalectomy in rats, suggesting therapeutic potential.

Pharmaceuticals
University of Zagreb
2w agoOpen Access
Level 5

Protective effects of BPC 157 in rats with experimentally induced lower extremity ischemia-reperfusion injury

Implication

Randomized trial evaluates BPC 157's protective effects in lower limb ischemia-reperfusion injury in rats, suggesting therapeutic potential.

Scientific Reports
Gazi University
3w agoOpen Access
Level 3: Clinical Trial

BPC-157 as an Investigational Peptide Therapeutic: Biopharmaceutical Challenges, Formulation Strategies, and Translational Development Barriers

Implication

Narrative review evaluates BPC-157's formulation, pharmacokinetics, and development barriers in therapeutics, indicating critical gaps.

Pharmaceutics
Carol Davila University of Medicine and Pharmacy
12w agoOpen Access
Level 5: Review

Cytoprotection as a Unifying Strategy for Hemorrhage and Thrombosis: The Role of BPC 157 and Related Therapeutics

Implication

Review demonstrates that cytoprotection reduces hemorrhage and thrombosis in rodent models, indicating BPC 157's promise for wound healing.

#cytoprotection#hemorrhage#thrombosis
Pharmaceuticals
University of Zagreb
5w agoOpen Access
Level 5

Endothelium-Dependent Nitric Oxide-Mediated Vasorelaxant Effects of BPC 157 in Human Internal Mammary Artery

Implication

Experimental results reveal BPC 157 reduces vascular tone in human arteries, suggesting its endothelial NO-mediated vasorelaxant potential.

#area-under-curve#cytoprotection#vascular-tone
Journal of Clinical Medicine
Hacettepe University
9w ago
Top Journal
Level 3: Early-Phase Trial

Down Regulation of HPV 16 and NF-KB with APG-157 in Head and Neck Cancer

Implication

Phase 2A clinical trial evaluates APG-157's effect on HPV 16 and immune markers in head and neck cancer, suggesting therapeutic potential.

Cancer Research
University of California, Los Angeles
2w agoOpen AccessPreprint
Preprint
Level 5: Review

Research Peptides for Sale: Quality Standards for BPC-157, TB-500, Sermorelin and Epitalon Procurement

Implication

Technical review outlines quality verification standards for research peptides, suggesting improved procurement processes.

BioChem Technology (United States)

Researchers studying BPC-157

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