GLP-1 receptor agonists

Also known as: GLP-1 RA, glucagon-like peptide-1, incretin-based therapy

GLP-1 receptor agonists in cardiometabolic and obesity research, including cardiovascular outcome trials and mechanistic studies.

GLP-1 receptor agonists research graphical abstract
Research landscape graphic for GLP-1 receptor agonists; Synapse pages are informational and not medical advice.

What does the research say about GLP-1 receptor agonists?

The GLP-1 class spans semaglutide, liraglutide, and dual incretin agents. Synapse aggregates trials, outcomes studies, and mechanistic papers tagged to GLP-1 pharmacology and related MeSH concepts.

Synapse surfaces peer-reviewed research and researcher networks for informational purposes only. This page does not provide medical advice, dosing guidance, or treatment recommendations.

Research feed: GLP-1 receptor agonists

11 indexed papers matched to curated MeSH concepts in the last 90 days.

10w ago
Top JournalNEJM Highlight
Level 5

GLP-1 Receptor Agonists

Implication

Controlled trials show GLP-1 receptor agonists reduce cardiovascular risk and improve metabolic outcomes in diabetes and obesity, indicating broader therapeutic applications.

New England Journal of Medicine
Tufts University
5d agoOpen Access
Top Journal
Level 5

Patient Experiences With GLP-1 Receptor Agonists

Implication

Qualitative study explores patient experiences with GLP-1 receptor agonists, highlighting benefits, challenges, and support needs.

JAMA Network Open
Stanford University
6w ago
Level 5: Review

GLP-1 receptor agonists

Implication

Review explores GLP-1 receptor agonists' benefits and challenges for nurse practitioners, highlighting prescription considerations.

The Nurse Practitioner
University of California San Francisco Medical Center
10w agoOpen Access
Top Journal
Level 1: Meta-Analysis

GLP-1 Receptor Agonists and Noncardiometabolic Outcomes

Implication

This umbrella review examines noncardiometabolic outcomes of GLP-1 receptor agonists, suggesting implications for safety and health associations.

JAMA Network Open
China Medical University
10w agoOpen Access
Level 3: Clinical Trial

GLP-1 Receptor Agonists and the Risk of Cholelithiasis: A Literature Review

Implication

Literature review examines gallstone risks in obese populations treated with GLP-1 receptor agonists, suggesting implications for patient management.

International Journal of Innovative Technologies in Social Science
Anhui Provincial Hospital
5w ago
Level 5: Case Report

A Case of GLP-1 Receptor Agonist-Induced Lithium Neurotoxicity

The report describes a case of GLP-1 RA-induced lithium neurotoxicity, suggesting a need for enhanced surveillance when coadministering these medications.

Implication

Requires close lithium monitoring with GLP-1 RA initiation or switches in bipolar patients; leaves open interaction mechanisms pending pharmacokinetic studies.**[[1]](https://www.researchgate.

Journal of Psychiatric Practice
The University of Texas Southwestern Medical Center
4w ago
Level 2: Phase 3 Trial

What obgyns need to know about GLP-1 receptor agonists

Implication

Review highlights safety and efficacy of GLP-1 receptor agonists in women's health, particularly in PCOS and pregnancy.

Current Opinion in Obstetrics & Gynecology
Flushing Hospital Medical Center
8w agoOpen Access
Level 3: Cohort Study

The Effect of GLP-1 Receptor Agonists on Epilepsy: No Appetite for Seizures

GLP-1 RAs linked to ~16% lower incident epilepsy risk in T2D vs other therapies.

Implication

May warrant GLP-1 RA preference in type 2 diabetes at epilepsy risk; leaves open causality pending randomized trials.

Epiliepsy currents/Epilepsy currents
Emory University
4w agoOpen Access
Trending on XTop Journal
Level 4: Retrospective

Survival and Recurrence With GLP-1 Receptor Agonists in Breast Cancer

Implication

Retrospective cohort study evaluates GLP-1 RA effects on survival in breast cancer, indicating potential benefits.

JAMA Network Open
University of Virginia
22w agoOpen Access
Level 3: Clinical Trial

GLP-1 Receptor Agonists and Clinical Periodontal Outcomes: A Scoping Review

Implication

Scoping review maps clinical oral and periodontal outcomes in humans receiving GLP-1 receptor agonists, suggesting important implications for oral health.

Researchers studying GLP-1 receptor agonists

Researcher network data is loading or unavailable for this topic.

Follow GLP-1 receptor agonists literature with AI-enriched clinical evidence on Synapse.

Search GLP-1 receptor agonists on Synapse

Powered by Synapse — AI-enriched analysis of 600,000+ peer-reviewed papers