Semaglutide

Also known as: Ozempic, Wegovy, Rybelsus

Peer-reviewed research on semaglutide across obesity, type 2 diabetes, and cardiovascular outcome trials.

Semaglutide research graphical abstract
Research landscape graphic for Semaglutide; Synapse pages are informational and not medical advice.

What does the research say about Semaglutide?

Semaglutide is among the most studied GLP-1 receptor agonists. Literature spans SELECT, SUSTAIN, STEP, and mechanistic work on receptor signaling and adipose/ cardiovascular endpoints.

Synapse surfaces peer-reviewed research and researcher networks for informational purposes only. This page does not provide medical advice, dosing guidance, or treatment recommendations.

Research feed: Semaglutide

11 indexed papers matched to curated MeSH concepts in the last 90 days.

22w agoOpen Access
Level 5

Readability and understandability of online patient education on semaglutide

Implication

Evaluative analysis of readability and understandability in online semaglutide education, indicating a need for revision.

Health Informatics Journal
University of Tennessee at Knoxville
22w agoOpen Access
Level 5: Literature Review

Semaglutide in the Era of Blockbuster Pharmaceuticals: A Narrative Review of Clinical, Economic, and Policy Dimensions

Implication

Narrative review examines semaglutide's clinical benefits and economic impact, highlighting regulatory challenges.

University of East Sarajevo
Klinika za psihijatriju Vrapče
14w ago
Top Journal
Level 3: Cohort Study

05 Effect Of Semaglutide Formulations On QTc Interval: A Retrospective Comparison Of Wegovy And Ozempic In A Tertiary Care Hospital

КАРДИОЛОГИЯ УЗБЕКИСТАНА
SUNY Upstate Medical University
13w ago
Top Journal
Level 3: Cohort Study

Ischemic optic neuropathy with semaglutide: global observational analysis of sex- and formulation-specific risk

Implication

Observational analysis reveals sex- and formulation-specific risk of ischemic optic neuropathy with semaglutide, suggesting important safety concerns.

British Journal of Ophthalmology
University of Toronto
14w ago
Level 5: Review

Semaglutide Hype or Hope: Evidence-based Review in Diabesity

Implication

Review highlights Semaglutide's impact on glycemic control and safety in type 2 diabetes, suggesting effective management for diabesity.

#semaglutide#diabetes#glycemic-control
Journal of the Association of Physicians of India
National Diabetes Obesity and Cholesterol Foundation
5d ago
Top Journal
Level 4: Cross-Sectional

2657-P: Who Shapes the GLP-1 Narrative on TikTok: A Cross-Sectional Content Analysis

Implication

Cross-sectional analysis identifies engaging GLP-1 content themes from TikTok creators, suggesting implications for patient education.

Diabetes
University of Baltimore
1w agoOpen Access
Top Journal
Level 5

Shrinking appetites: Will GLP-1 adoption in high-income countries accelerate Big Food’s push into low- and middle-income countries?

Implication

Randomized trial shows potential GLP-1 demand shift could worsen diet-related diseases in LMICs, indicating policy intervention is needed.

Globalization and Health
International Center for Tropical Agriculture
22w agoOpen Access
Level 5: Case Report

Semaglutide-associated Twiddler syndrome.

Semaglutide-induced rapid weight loss of 25 kg in a patient with an ICD led to Twiddler syndrome and right ventricular lead dysfunction.

Implication

May warrant monitoring in semaglutide-treated device patients; hypothesis-generating case report leaves need for prospective confirmation open.

Diabetes Australia
10w ago
Level 5

The “Ozempic® Limb”

Implication

Case reports demonstrate complications from GLP-1 RAs in individuals with prosthetic limbs, suggesting the need for tailored treatment strategies.

American Journal of Physical Medicine & Rehabilitation
Western University
7w ago
Level 5

From Weight Loss to Legal Loss: How Wegovy Exposed a Hidden Patent Exception

Implication

This article evaluates patent gaps in drug compounding under US law, suggesting potential reforms.

GRUR International

Researchers studying Semaglutide

Researcher network data is loading or unavailable for this topic.

Follow Semaglutide literature with AI-enriched clinical evidence on Synapse.

Search Semaglutide on Synapse

Powered by Synapse — AI-enriched analysis of 600,000+ peer-reviewed papers