Tirzepatide

Also known as: Mounjaro, Zepbound, dual GIP/GLP-1

Research on tirzepatide, a dual GIP/GLP-1 receptor agonist, including SURPASS, SURMOUNT, and cardiovascular-focused substudies.

Tirzepatide research graphical abstract
Research landscape graphic for Tirzepatide; Synapse pages are informational and not medical advice.

What does the research say about Tirzepatide?

Tirzepatide combines GIP and GLP-1 activity. Published work covers glycemic control, weight reduction, sleep apnea substudies, and emerging cardiovascular outcome readouts.

Synapse surfaces peer-reviewed research and researcher networks for informational purposes only. This page does not provide medical advice, dosing guidance, or treatment recommendations.

Research feed: Tirzepatide

11 indexed papers matched to curated MeSH concepts in the last 90 days.

5d ago
Top Journal
Level 4: Cross-Sectional

2657-P: Who Shapes the GLP-1 Narrative on TikTok: A Cross-Sectional Content Analysis

Implication

Cross-sectional analysis identifies engaging GLP-1 content themes from TikTok creators, suggesting implications for patient education.

Diabetes
University of Baltimore
10w agoOpen Access
Level 3: Clinical Trial

Tirzepatide in Egypt: A New Era in Type 2 Diabetes and Obesity Management

Implication

This review analyzes tirzepatide's effectiveness in managing type 2 diabetes and obesity, suggesting significant implications for treatment in Egypt.

Mansoura University
8w agoOpen Access
Level 5

Tirzepatide-associated interstitial kidney injury

Implication

Case report reveals worsening renal function in a patient using tirzepatide, suggesting potential nephrotoxicity.

#interstitial-nephritis#renal-function#glomerular-filtration-rate
JCEM Case Reports
Cleveland Clinic
10w agoOpen Access
Level 5

Predictors and Characteristics of Hair Loss Among Users of GLP ‐1 Receptor Agonists: A Cross‐Sectional Analysis

Implication

Cross-sectional analysis reveals predictors of hair loss in GLP-1 receptor agonist users, suggesting key clinical implications.

Journal of Cosmetic Dermatology
King Saud bin Abdulaziz University for Health Sciences
5w ago
Level 5

A Case of GLP-1 Receptor Agonist-Induced Dysphoria and Aggression in a Patient With Underlying Major Depressive Disorder

Implication

Case report highlights the psychiatric side effects of GLP-1 receptor agonists in a patient with depression, suggesting caution in their use.

Journal of Psychiatric Practice
The University of Texas Southwestern Medical Center
10w ago
Level 5: Case Report

Drug-induced liver injury secondary to tirzepatide

Implication

Case report shows hepatotoxicity from tirzepatide in a young woman, indicating potential risks of this drug.

BMJ Case Reports
Griffith University
10w ago
Level 4: Cross-Sectional

Prevalence of Obesity Medications in the Military Health System: An Update from 2022

Implication

Cross-sectional analysis reveals low utilization of obesity medications among military beneficiaries, suggesting potential barriers to access.

Military Medicine
Uniformed Services University of the Health Sciences
2w ago
Level 3: Clinical Trial

Tirzepatide data: safety always comes first!

Implication

Review evaluates tirzepatide’s efficacy and safety in type 2 diabetes and obesity, highlighting implications for prescription practices.

Expert Opinion on Drug Safety
University of Ljubljana
12w agoOpen Access
Level 5

Attitudes Toward Injectable GLP‐1 Drugs for Obesity Treatment: A Qualitative Interview Study With Healthcare Professionals

Implication

Qualitative interviews reveal healthcare professionals' views on prescribing GLP-1 drugs for obesity treatment, indicating gaps and concerns.

Obesity Science & Practice
University College London
3w agoOpen AccessPreprint
Preprint
Level 2: Phase 3 Trial

ITU Tier 1+ #32: Pharmaceuticals (Kₚharma)

Implication

Randomized trial evaluates pharmaceutical efficacy in pipelines, indicating promising AI integrations.

Stroke Association

Researchers studying Tirzepatide

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