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Outcomes of Transcatheter Tricuspid Edge-to-Edge Repair and Transcatheter Valve Replacement for Severe Tricuspid Regurgitation: A Systematic Review and Meta-Analysis
How do safety and clinical outcomes compare between transcatheter tricuspid edge-to-edge repair and transcatheter tricuspid valve replacement in patients with severe tricuspid regurgitation?
Result: T-TEER was associated with very low in-hospital (0.13%) and 30-day (0.46%) mortality, whereas TTVR had higher early mortality but similar 1-year mortality, achieved more complete TR elimination, but had higher rates of permanent pacemaker implantation, thrombotic events, and major bleeding.
“Real-World Outcomes of Transcatheter Tricuspid Valve Replacement https://t.co/594BIM51cc”
Bisoprolol vs. Carvedilol After Percutaneous Coronary Intervention in Acute Myocardial Infarction With Reduced Left Ventricular Ejection Fraction
Comparative analysis shows similar cardiovascular outcomes in patients with AMI using bisoprolol or carvedilol, suggesting both are viable for prevention.
“In AMI patients with reduced LVEF undergoing PCI, bisoprolol and carvedilol showed comparable 3-year cardiovascular outcomes. Both are suitable options for secondary prevention. By Jun-Chang Jeong https://t.co/RfYpwnawv9 #circ_j #CardioX https://t.co/WrQyGDbODQ”
Targeted Exome Sequencing in Pre-Hospital Sudden Cardiac Arrest Reveals a High Genetic Diagnostic Yield
Does whole-exome sequencing identify clinically relevant genetic variants in young and middle-aged adults with pre-hospital sudden cardiac arrest?
Result: Pathogenic or likely pathogenic variants were identified in 13 individuals, corresponding to a diagnostic yield of 18.8%.
Infective endocarditis in hypertrophic cardiomyopathy: a real-world matched cohort analysis
Does hypertrophic cardiomyopathy increase the risk of infective endocarditis compared to matched controls?
Result: The 5-year cumulative incidence of IE was 3.25% in the HCM group and 1.31% in controls (HR 2.62, 95% CI 2.20 to 3.12, p<0.001).
Rate control treatment with calcium channel blockers and beta blockers for patients with atrial fibrillation: a systematic review and meta-analysis
A systematic review compares heart rate control in atrial fibrillation using beta blockers and calcium channel blockers, suggesting similar efficacy with some differences.
Study Design and Rationale of the Visualizing Subclinical Myocardial Changes with Shear Wave Elastography in Dilated Cardiomyopathy (VISUALIZE-DCM) Trial
Prospective trial evaluates shear wave elastography for detecting myocardial fibrosis in dilated cardiomyopathy, suggesting new risk stratification tools.
Orai1 Facilitates Angiogenesis After Myocardial Infarction Through Notch1 Signaling Pathway
This research highlights Orai1's role in promoting angiogenesis after myocardial infarction, suggesting it as a therapeutic target.
Infections of Selected Nonvalvular Cardiovascular Devices: A ScienceAdvisory From the American Heart Association
Key Finding: Nonvalvular cardiovascular device infections are addressed in a new American Heart Association advisory that provides an evaluation algorithm for patients with bloodstream infections.
“Published today, Infections of Selected Nonvalvular Cardiovascular Devices: A Science Advisory from the American Heart Association. Nonvalvular CV device infections including intracardiac devices (e.g., septal closure devices, shunts), intravascular devices (e.g., stents, https://t.co/4KHI1JL4m4”
Randomized Trial of Adjunctive Prednisolone for Kawasaki Disease
Key Finding: Adjunctive prednisolone added to standard primary treatment for Kawasaki disease did not reduce the incidence of coronary-artery lesions at 1 month after illness onset.
“なんとNEJM Randomized Trial of Adjunctive Prednisolone for Kawasaki Disease | New England Journal of Medicine https://t.co/lXJVbmWINA”
The Natural History of Massive Left Ventricular Hypertrophy in Pediatric Hypertrophic Cardiomyopathy: A Multiregistry Analysis
Multiregistry analysis reveals MLVH in early diagnosed pediatric patients, indicating a significant regression in some cases.