Class 2 obesity was associated with a 2.1-fold and class 3 obesity with a 3.0-fold increased risk of heart failure compared to normal weight individuals.
PRMT9 overexpression in macrophages reduced infarct size and improved cardiac function after MI by facilitating STAT1 degradation and suppressing M1-like polarization.
Spontaneous myocardial infarction occurred more frequently after PCI (6.8%) than CABG (3.4%) and was a strong predictor of cardiovascular mortality (adjHR 9.39).
In patients with diabetes and multivessel disease undergoing PCI, ticagrelor was not noninferior to prasugrel for the composite primary outcome at 1 year (16.6% vs 14.2%; P = .12).
A standardized framework for evaluating predictive models and biomarkers is essential for improving cardiovascular disease prevention in diverse populations.
Atherosclerotic cardiovascular disease and cancer share risk factors and mechanisms, requiring a multidisciplinary approach to screening and management in affected patients.
A randomized clinical trial demonstrates improved sinus rhythm restoration in patients using a handheld device for Valsalva maneuver.
Driver ablation in patients with persistent atrial fibrillation resulted in 90% freedom from atrial fibrillation after 2 years of follow-up.
A meta-analysis compares 5-year outcomes of TAVI and SAVR in low- to intermediate-risk patients, indicating SAVR may be superior.
A systematic review assesses survival benefits of guideline-directed therapy in older heart failure patients, suggesting improvements are needed.