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cohort · n=8277 إشارةExpert CommentaryTrending on X
11 أغسطسGriffithsCirculation
Pediatric Pulmonary Hypertension International Risk Score predicts one-year major adverse events with 0.90 AUC.
Pediatric PH risk model may refine prognostication; leaves open whether it improves outcomes over expert opinion or adult-derived tools.
RCT · n=1,2221 إشارة
10 أغسطسPárragaCardiovascular Diabetology
Dapagliflozin cuts mortality or worsening heart failure ~42% vs standard care in diabetic TAVR patients.
Benefit consistent across DM status post-TAVR; leaves open dedicated trials to confirm DM-specific effects.
RCT11 إشارةTrending on X
12 أغسطسJhanjiJAMA
Total intravenous anesthesia did not improve days alive and at home at 30 days compared with inhalational anesthesia for major noncardiac surgery (IRR 1.00; 95% CI 0.99-1.02; P=.68).
TIVA confers no recovery advantage over inhalational anesthesia; supports either approach in older adults undergoing major noncardiac surgery.
DBDr. Bernard
Anesthesiologist, Unknown
First of all, congratulations both to Joyce, Shaman, and the people group, you know, and the U.K. for actually executing this trial and recruiting. So it's a fabulous feat. I think as you said, it's absolutely a positive study... in the sense that it's reassuring that the techniques that are available to us as a community... it's absolutely reassuring that whatever anesthetic choice we have available to us, patients will do well.
cohort · n=1,6953 إشارةTrending on X
11 أغسطسAnastasiaEuropean Heart Journal - Valvular and Structural Heart Disease
Low eGFR linked to ~28% higher 1-year major event risk in TAVR patients with severe PAD.
CKD heightens peri-procedural risks in severe PAD patients undergoing TAVR; leaves open whether optimization improves outcomes.
cohort · n=1478 إشارةTrending on X
10 أغسطسCirculation Heart Failure
AI-enabled ECG tool predicts left ventricular systolic dysfunction with 100% sensitivity.
AI-ECG may ease LVSD monitoring in mavacamten-treated HCM; leaves open prospective validation before altering TTE surveillance.
systematic_review · n=68,6111 إشارة
10 أغسطسCureus
Resuming DOACs after GI bleeding in AF avoids rebleeding while linked to lower thromboembolism and mortality.
Optimal DOAC restart timing after GIB in AF remains unclear from observational data; leaves open the need for randomized trials.
Human Clinical TrialExpert Commentary
13 أغسطسAggarwalCirculation Research
Current antiplatelet treatment paradigms do not fully account for biological heterogeneity in platelet function, highlighting the need for sex-specific considerations and personalized therapy.
Platelet response heterogeneity may modulate ischemic and bleeding risks; leaves open whether tailored antiplatelet regimens improve outcomes.
cohort · n=2023 إشارةTrending on XTrending on X
10 أغسطسSongSunhwan'gi
LQT2 and LQT3 genotypes linked to ~450% higher life-threatening arrhythmia risk versus LQT1 in pediatric LQTS.
May inform risk assessment in Korean children with LQTS; extends sparse Asian data but leaves generalizability open.
cohort · n=406 إشارةTrending on X
10 أغسطسMasudaJournal of Cardiovascular Electrophysiology
QDOT MICRO microelectrodes record ~130% higher local electrogram voltages at conduction gaps versus conventional electrodes.
Microelectrodes may enhance gap detection during ablation; hypothesis-generating and should not yet change practice.
cohort · n=3394 إشارةTrending on X
10 أغسطسOdaCirculation Journal
PFA for AF shows no pulmonary vein stenosis versus a 16% incidence with RFA.
Emphasizes surveillance gaps after AF ablation; leaves open true PV stenosis incidence without routine imaging.
