Ask Anything
ESC 2026 DiscussionExplore the Hot Line trials, expert perspectives, and key takeawaysExplore the discussion→Hot Research Today
Papers from every journal, all in one place. Create custom feeds.
cohort · n=94,516Trending on X
SEP 11LiangBMJ
New Zealand CVD risk equations calibrate poorly in Chinese diabetes cohorts but improve with age adjustments.
CVD risk equations may not generalize across high- and non-high-income settings in diabetes; leaves open need for local derivation and validation.
cohort · n=921 mentionsTrending on X
SEP 10QianCirculation Heart Failure
CRT is linked to an ~11% LVEF improvement at 12 months and reduced ketone bodies.
CRT-linked metabolomic shifts in HFrEF may indicate better substrate use; hypothesis-generating for response prediction, needs prospective validation.
cohort · n=3,1171 mentionsTrending on X
SEP 10BalakrishnanCirculation Heart Failure
LMNA genotype linked to ~452% higher incident AF risk vs genotype-negative DCM patients.
LMNA carriers with dilated cardiomyopathy may warrant closer AF monitoring; extends genotype-specific risk data but leaves practice change open pending trials.
cohort · n=1,852Trending on X
SEP 10IzumiCirculation Heart Failure
Cardiac sarcoidosis recurrence linked to ~38% higher risk of death, HF, or fatal arrhythmias.
Recurrence identifies higher-risk patients; leaves open whether intensified monitoring or therapy improves outcomes.
cohort · n=2,1552 mentionsTrending on X
SEP 11ScottiCirculation Cardiovascular Interventions
Severe TR linked to ~101% higher 2-year all-cause mortality versus moderate or less TR.
Baseline severe TR doubles mortality risk after successful M-TEER; leaves open whether TR-directed intervention improves outcomes.
cohort · n=553
SEP 11ZaidCirculation Cardiovascular Interventions
Reintervention for failed balloon-expandable valves shows similar mortality to self-expanding valves.
Comparable reintervention mortality irrespective of initial valve type supports standardized approaches; leaves open mechanism-specific prospective trials.
cohort · n=3633 mentionsTrending on X
SEP 10WienemannCirculation Cardiovascular Interventions
Transfemoral Trilogy TAVR achieves 98% technical success in symptomatic aortic regurgitation.
Real-world data support Trilogy TAVR feasibility in AR; leaves open need for RCTs on durability and outcomes.
RCT1 mentionsTrending on X
SEP 11GalaJournal of Interventional Cardiac Electrophysiology
Efficacy and safety of pulsed-field ablation with the pentaspline catheter versus thermal ablation in paroxysmal atrial fibrillation: a meta-analysis of randomised controlled trials
Meta-analysis of randomized trials demonstrates the efficacy and safety of pulsed-field ablation in paroxysmal atrial fibrillation, highlighting a viable non-thermal alternative.
meta-analysis · n=5,9781 mentionsTrending on X
SEP 11ZhangFrontiers in Endocrinology
Higher triglyceride-glucose index is linked to ~62% greater MACE risk per unit after CABG.
May aid post-CABG risk stratification as a metabolic marker; extends observational evidence on TyG prognostic value.
meta-analysis · n=2,324
SEP 10KarthikeyanCardiology in Review
Discontinuing OAC ≥6 months post-ablation cuts major bleeding ~67% without increasing stroke or embolism.
Supports OAC discontinuation after successful AF ablation without excess stroke; challenges guidelines recommending indefinite therapy based on risk scores alone.
