ESC 2026 DiscussionExplore the Hot Line trials, expert perspectives, and key takeawaysExplore the discussion→Papers from every journal, all in one place. Create custom feeds.
Offers structured fit-for-duty guidance for tactical athletes; extends prior competitive sports cardiology frameworks to military, law enforcement, and firefighter populations.

Supports recommending frequent short breaks from sitting to enhance peripheral hemodynamics; extends evidence for sedentary interruption on vascular outcomes.
PCI confers no mortality benefit in TAVI candidates with CAD; challenges routine revascularization and supports selective deferral.

May support ticagrelor-aspirin for functional benefit in multiple-infarct stroke after thrombolysis; extends TAPIS but remains hypothesis-generating pending confirmation.

May support PRS for HCM risk stratification; extends prior GWAS to SCD prediction in sarcomere-negative cases.
Automated scoring may match manual HFpEF diagnostic accuracy; extends deep learning echo validation but leaves prospective adoption open.

Direct transfer associated with lower OHCA mortality; hypothesis-generating and requires randomized confirmation before practice change.

Supports acute PVI feasibility with pear two-step PFA in this cohort; leaves open durability, safety, and efficacy for randomized trials.

Supports culprit optimization in contemporary AMI practice; leaves open optimal non-culprit strategies in multivessel disease.
No consistent aspiration risk elevation supports continuing GLP-1 RAs perioperatively; leaves open need for RCTs given low-certainty evidence.
