ESC 2026 DiscussionExplore the Hot Line trials, expert perspectives, and key takeawaysExplore the discussion→Papers from every journal, all in one place. Create custom feeds.
What was less expected was that persons with frailty appeared to derive greater benefits on how they felt and functioned (eg, mobility appeared to improve more with semaglutide in persons with frailty); and that, compared with placebo, persons with greater frailty were actually less likely to dis...
JAMA Cardiology
Mandates heritage-specific screening and interventions for Hispanic adults; challenges the Hispanic paradox as an oversimplification requiring disaggregated data.
Video-based education matches nurse-guided pamphlets for home BP skills in stage 3–4 CKD; supports equivalent efficacy of scalable digital versus traditional education.
Consider limb size and BP when setting occlusion pressures; heterogeneity leaves standardization open for prospective trials.
DUTCH-WAIST will test semaglutide for rhythm control in overweight persistent AF; leaves open whether GLP-1 RAs improve arrhythmia outcomes pending RCT results.
May warrant closer monitoring in elderly patients with vaccine myocarditis; hypothesis-generating and requires prospective confirmation.
Minicrush was associated with lower stent thrombosis than TAP without differing target lesion failure; leaves open need for randomized confirmation in bifurcation PCI.
Meta-analytic correspondence reveals robust efficacy across pooled prasugrel doses in acute coronary syndrome, supporting flexible antiplatelet evaluation strategies.
Network meta-analysis reveals comparative outcomes of pooled prasugrel doses in acute coronary syndrome, indicating significant trade-offs between efficacy and bleeding.
Clinicians should assess digital literacy and offer guided resources; leaves open development of evidence-based guidelines for heart failure digital tools.
