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Prognostic Impact of Quantitative Flow Ratio-Derived Physiology for Intermediate Non-Infarct-Related Artery in Acute Myocardial Infarction
Does QFR-derived physiology stratify high-risk non-infarct-related arteries and guide treatment in patients with acute myocardial infarction?
Result: QFR-derived physiology, including QFR and QFR-PPG, can stratify high-risk non-IRAs and guide optimal treatment in patients with AMI.
“In AMI, combining QFR with QFR-PPG unmasked high-risk non-IRA lesions. Deferred high-risk lesions had strikingly worse 3-year outcomes, whereas PCI was associated with better prognosis in this subgroup. By Sho Nakao https://t.co/PgqtOWqqUH #circ_j #CardioX https://t.co/BGol4BwiFb”
From Caging to Uncaging With Bioadaptors: A Novel Paradigm in Coronary Revascularization
Does the DynamX coronary bioadaptor improve clinical outcomes and restore vessel function compared to conventional drug-eluting stents in patients with coronary artery disease?
Result: The DynamX coronary bioadaptor demonstrated noninferiority to drug-eluting stents with superior late lumen preservation, reduced neointimal hyperplasia, and low target-lesion failure rates, while restoring vessel pulsatility and compliance after 6 months.
“From Caging to Uncaging With Bioadaptors: A Novel Paradigm in Coronary Revascularization | Journal of the American Heart Association https://t.co/umPCKN5822”
In-Hospital and Long-Term Clinical Outcomes in Patients With Acute Myocardial Infarction Categorized as SCAI Shock Stage B
Do in-hospital and long-term clinical outcomes differ between acute myocardial infarction patients categorized as SCAI shock stage B versus stage A?
“As compared to SCAI shock modified stage A, modified stage B was not independently associated with in-hospital and long-term clinical outcomes in patients with acute myocardial infarction. By Hisashi Sato and Kenichi Sakakura https://t.co/hM33b1dxhl #circ_rep #CardioX https://t.co/eRcVmgFz7C”
Contribution of Non-Sustained Ventricular Tachycardia to the Primary Prevention of Sudden Cardiac Death ― Validation of Current Japanese Circulation Society / Japanese Heart Rhythm Society Guideline Recommendations in the Nippon Storm Study ―
Does non-sustained ventricular tachycardia (NSVT) predict sudden cardiac death in Japanese patients receiving ICDs for primary prevention?
This study aims to validate the prognostic significance of non-sustained ventricular tachycardia in Japanese patients receiving ICDs for primary prevention.
“A history of NSVT showed limited prognostic value for primary prevention ICD therapy. Holter-documented NSVT modestly predicted appropriate ICD therapy but was not associated with VF or mortality. By Ryobun Yasuoka https://t.co/DB7T6avwKb #circ_j #CardioX https://t.co/JJIixfQYXM”
Heart Failure Guideline-Directed Medical Therapy Scoring Systems: A Scoping Review
Result: Key gaps in GDMT scores include heterogeneous weighting of drug classes and doses, minimal incorporation of intolerance to identify maximum-tolerated therapy, and heterogeneous incorporation of therapies beyond quadruple therapy.
“Heart Failure Guideline-Directed Medical Therapy Scoring Systems: A Scoping Review Multiple, disparate scores have been developed to quantify heart failure with reduced ejection fraction GDMT optimization, undermining the original intent. Key gaps in scores include heterogeneous https://t.co/mmJrpNC96G”
Which Is Better? Pedicled versus Skeletonized Internal Mammary Artery Grafts in Coronary Artery Bypass Grafting: Emphasis on the Antispastic Role of Perivascular Adipose
Does pedicled internal mammary artery harvesting improve vasorelaxation and clinical outcomes compared to skeletonized harvesting in patients undergoing CABG?
Result: Preservation of perivascular adipose tissue definitively preserves vasorelaxation properties of the IMA, and clinical studies suggest skeletonized harvesting is associated with a higher rate of graft occlusion and worse clinical outcomes than the pedicled technique.
Mycn Reactivates the Cell Cycle in Adult Cardiomyocytes and Promotes Cardioprotection in Myocardial Infarction
Result: Mycn reactivates the cardiomyocyte cell cycle and promotes cardioprotection following ischemic injury, likely via induction of a neonatal-like transcriptional program.
Risk factor profiles and haemodynamic progression in aortic stenosis: a retrospective population-based study
Result: Rapid progression occurred in 7.8% of patients with aortic sclerosis, 16.4% with mild AS and 29.8% with moderate AS.
Care and Outcomes of New‐Onset Heart Failure Across Vulnerable Populations: Temporal Trends in Mortality and Treatment in a Danish Nationwide Cohort From 2003 to 2022
Do temporal trends in mortality and treatment initiation for new-onset heart failure differ across vulnerable populations compared to their non-vulnerable counterparts?
Result: Overall mortality risk declined over the past 2 decades, but 4 out of 8 vulnerable groups experienced a lesser decline than their counterparts, and 6 vulnerable groups still had worse outcomes at the end of the study period.
Multifaceted Strategies for Hypertension Control in Low-Income Patients
Does a multifaceted, team-based implementation strategy reduce systolic blood pressure in low-income patients with hypertension?
Result: A multifaceted, team-based implementation strategy resulted in a significantly greater reduction in systolic blood pressure than enhanced usual care.
“Original Article: Multifaceted Strategies for Hypertension Control in Low-Income Patients (IMPACTS-BP trial) https://t.co/AxUONCq718 Editorial: Systems-Based Success for Hypertension https://t.co/4BkINWpImo #Cardiology https://t.co/AXDHJVmxfl”
Hypertension is a major public health priority due to its high prevalence and associated morbidity and mortality. Low-income populations experience higher prevalence and lower control rates, which [contribute] to health disparities.