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RCT · n=2,50811 mentionsTrending on X
AUG 12JhanjiJAMA
Total intravenous anesthesia fails to improve days alive and at home versus inhalational anesthesia.
TIVA confers no recovery advantage over inhalational anesthesia; supports either approach in older adults undergoing major noncardiac surgery.
DBDr. Bernard
Anesthesiologist, Unknown
First of all, congratulations both to Joyce, Shaman, and the people group, you know, and the U.K. for actually executing this trial and recruiting. So it's a fabulous feat. I think as you said, it's absolutely a positive study... in the sense that it's reassuring that the techniques that are available to us as a community... it's absolutely reassuring that whatever anesthetic choice we have available to us, patients will do well.
cohort · n=4,1611 mentions
AUG 12Yoonnpj Digital Medicine
Sacubitril/valsartan linked to ~18% fewer major events vs. valsartan in a machine learning-identified HFpEF phenotype.
May support phenotype-guided sacubitril/valsartan in HFpEF; leaves open prospective validation before practice change.
Meta-Analysis1 mentions
AUG 14BaeJournal of Clinical Medicine
Prognostic Value of CT-Based Coronary Imaging for Perioperative Cardiovascular Risk Stratification Before Noncardiac Surgery: An Updated Systematic Review and Meta-Analysis
Meta-analysis reveals coronary CT markers predict perioperative major adverse cardiac events in noncardiac surgery, indicating strong value for preoperative cardiovascular risk stratification.
cohort · n=5,528,397Trending on X
AUG 12KhanJACC Advances
Renal disease linked to ~39% higher 30-day readmission and increased mortality following AF hospitalization.
National AF hospitalization trends reported; leaves open causal factors and targeted interventions to reduce readmissions.
Systematic Review2 mentionsTrending on X
AUG 14WuExpert Review of Pharmacoeconomics & Outcomes Research
Machine learning-based prediction of cardiovascular adverse events in patients with cancer: a systematic review
INTRODUCTION: Cardiovascular (CV) adverse events are increasingly recognized in patients with cancer. Previous reviews of AI/ML have focused on single cancer types, imaging-based data, and lacked evaluation of methodological rigor. This systematic review synthesized AI/ML models developed to predict CV adverse events from patient-level clinical data across diverse cancer populations. METHODS: This review followed the PRISMA 2020 guidelines. PubMed and Web of Science were searched through 26 October 2025. Study characteristics, model development, and handling of features and missing data were extracted. Study quality was assessed using the IJMEDI checklist. RESULTS: Of 32 included studies, 18 compared multiple algorithms and 14 used a single algorithm. Random forest and XGBoost were the most common methods (n = 17, respectively), and XGBoost was most often the best-performing model in multi-algorithm studies, although substantial study heterogeneity precludes concluding general algorithmic superiority. Common limitations were unreported missing data handling (n = 17), limited external validation (n = 8), and rare calibration assessment (n = 4). Most studies were rated medium quality (n = 28). CONCLUSIONS: AI/ML models show promise for predicting CV adverse events in patients with cancer; however, clinical applicability is constrained by insufficient preprocessing transparency, limited external validation, and inadequate calibration reporting.
meta-analysis1 mentions
AUG 12ParamkusamAsian Cardiovascular and Thoracic Annals
Transseptal mitral surgery is linked to ~44% higher PPM risk versus left atrial approach.
TS approach linked to longer operative times and higher pacemaker risk than LA in MVS; extends pooled evidence favoring LA to minimize complications.
meta-analysis · n=13,4373 mentionsTrending on X
AUG 12SritharanNephrology Dialysis Transplantation
ARNI use in dialysis-dependent HFrEF is linked to ~22% lower all-cause mortality vs. non-ARNI regimens.
Supports ARNI consideration in dialysis HFrEF; extends observational evidence but leaves open need for RCTs.
RCT · n=2,5072 mentionsTrending on X
AUG 12FrempongAnaesthesia
Total intravenous anaesthesia shows comparable cost-effectiveness to inhalational anaesthesia.
May support either technique on cost-effectiveness grounds; leaves open confirmation in larger trials.
systematic_review8 mentionsTrending on X
AUG 12Ibarra-PesoMedicina
Omega-3 supplementation yields mixed effects on arterial stiffness but reduces PWV at moderately high doses.
May support 1.8–4 g/day omega-3 for arterial stiffness reduction; extends meta-analyses by clarifying dose heterogeneity.
systematic_review · n=1,1621 mentions
AUG 12KristinawatiSystematic Reviews
Nursing interventions combining education and support may improve selected HF self-care dimensions despite heterogeneous effects.
Supports COM-B-guided nursing programs in HF self-care; extends theory-driven intervention evidence for implementation trials.
