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RCT · n=17,60410 mentionsExpert CommentaryTrending on X
AUG 18PlutzkyCirculation
Semaglutide cuts hsCRP by ~38% and lowers MACE risk independent of weight loss and LDL.
Semaglutide may lower MACE in overweight patients with ASCVD without diabetes; leaves open long-term durability and broader applicability.
DJDr. Jorge Plutzky
Cardiologist, Brigham and Women's Hospital
The fact that you can see benefits within 3 to 6 months points to other mechanisms that may be involved more rapidly than what we would typically look at in terms of weight change. He suggested that it might relate to inflammation, noting that hs-CRP is reduced quite quickly after starting semaglutide.
Guideline5 mentionsExpert Commentary
AUG 17BenjaminCirculation Population Health and Outcomes
2026 AHA/ACC Clinical Performance and Quality Measures for Patients With Atrial Fibrillation: A Report of the American College of Cardiology/American Heart Association Joint Committee on Performance Measures
These 5 measures enable standardized, equitable AF quality assessment; extends guidelines into actionable public reporting and pay-for-performance standards.
meta-analysis · n=97,316
AUG 17BasileEuropean Heart Journal - Valvular and Structural Heart Disease
LAAO device embolization is rare at ~0.3% incidence but carries high mortality.
Emphasizes need for immediate post-LAAO monitoring; extends prior estimates but leaves optimal prevention strategies open.
RCT · n=651 mentions
AUG 17FudimESC Heart Failure
C-MIC therapy shows no benefit over control for GDMT adjustments in non-ischemic HFrEF.
No differential GDMT changes explain C-MIC benefits in HFrEF; confirms device effect independent of background therapy optimization.
RCT · n=6,0015 mentionsTrending on X
AUG 14OstrominskiEuropean Journal of Heart Failure
Finerenone consistently improved clinical outcomes compared to placebo across all baseline hypertension categories (Pinteraction=0.32), including in the 12.9% of patients with apparent treatment-resistant hypertension.
Finerenone may improve BP and outcomes in aTRH; extends FINEARTS-HF findings to this subgroup but leaves dedicated trials open.
JL
meta-analysis · n=3,2746 mentions
AUG 17RattkaJournal of Interventional Cardiac Electrophysiology
Combined CA and LAAC linked to ~56% higher arrhythmia recurrence versus CA alone.
One-stop CA+LAAC appears feasible in AF; leaves open whether combined use improves outcomes versus staged procedures.
meta-analysis · n=10,1001 mentions
AUG 14BaeJournal of Clinical Medicine
CCTA-detected obstructive CAD is linked to ~618% higher perioperative MACE risk.
May enhance preoperative risk stratification with coronary CT; extends observational data but leaves open need for prospective validation.
meta-analysis · n=77,5266 mentionsTrending on X
AUG 17RakabAging Clinical and Experimental Research
Short-term ECG screening increases new AF diagnoses ~76% but fails to reduce stroke or mortality.
Short-term ECG screening increases AF detection and OAC initiation without reducing stroke, mortality, or bleeding; leaves open the need for conclusive outcome trials.
DEDr. Elsayed Balbaa
Cardiology, Ain Shams University
While short-term and intermittent ECG-based AF screening in older adults without known AF increased AF detection, it did not improve clinical outcomes, including stroke and mortality.
cohort · n=1,1472 mentions
AUG 14EhrJACC Advances
Selective iliofemoral angiography after TF-TAVI shows similar vascular and access-site complications to routine angiography.
Selective angiography may suffice without excess major complications; leaves open whether routine use improves outcomes in randomized settings.
RCT · n=5121 mentions
AUG 17PassoCirculation Population Health and Outcomes
Multidomain cardiac rehabilitation cuts CV death or unplanned CV hospitalization ~43% in frail post-MI patients.
Supports multidomain cardiac rehabilitation in frail post-MI patients; extends evidence to this high-risk subgroup.