Ask Anything

Vaishnavi Kundel

General / Preventive / Lipids · Icahn School of Medicine at Mount Sinai

4d

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If approved to treat obstructive sleep apnea, orforglipron could be a promising oral pharmacologic option for people with overweight or obesity and this condition. A convenient daily pill may help expand access to treatment for sleep apnea, and it could potentially be used with CPAP or other therapies to better meet individual patient's needs.

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Our study shows that for many people who have already experienced an ischemic stroke or TIA, aiming for a systolic blood pressure below 120 mm Hg can provide additional cardiovascular protection compared with the conventional target of below 140 mm Hg. However, we emphasize that achieving lower blood pressure safely requires appropriate medical supervision and additional monitoring, particularly of kidney function.

Carolina Malta Hansen

Cross-Cutting Cardiology · University of Copenhagen

4d

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Changing how an entire community responds to cardiac arrest takes time, and our findings show just how challenging that can be. In the meantime, the message to the public remains simple: learn CPR, recognize the signs of cardiac arrest, call 9-1-1 immediately and follow the dispatcher's instructions. Everyone has the potential to save a life.

Gurleen Kaur

Lipoproteins and Cardiovascular Health · Chandigarh University

3d

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In TYDAL-TIMI 78 trial (phase 2b), ANGPLT4 inhibition was effective at ⬇️ triglyceride levels & was not associated w/ more adverse events compared to placebo. Greater reductions in TGs were seen in pts w/ ⬆️ baseline TG levels.

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We expected that the group with left bundle branch pacing would do better than the group with right ventricular pacing. However, the difference between the two groups was greater than we expected. This study shows that left bundle branch pacing should be the first choice for patients with heart block who need a pacemaker.

Otavio Berwanger

General Cardiology · University of Modena and Reggio Emilia

5d

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“These findings should not be interpreted as evidence that more intensive BP lowering is ineffective for people with Type 2 diabetes. Rather, they suggest that any cardiovascular benefit may be smaller than that observed in individuals without Type 2 diabetes.”

Jörg Hausleiter

Interventional / Structural Cardiology · LMU Klinikum

2mo

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Among these high-risk patients, transcatheter tricuspid valve repair on top of medical therapy resulted not only in quality-of-life improvements but also in meaningful and sustained reductions in hard clinical outcomes, which has not been demonstrated before with the intervention.

Dr. Viktor Kočka

Interventional / Structural Cardiology · Charles University

2mo

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Using the blueprint already employed for heart attacks, we were able to demonstrate that specialised interventional treatment can be delivered in tertiary care centres across our national network. This may pave the way for an improved, standardised approach to the treatment of pulmonary embolism, reducing the acute risks that patients face.