CCR8 + Tregs were essential for cardiac protection after myocardial infarction, as their deletion worsened cardiac function and increased inflammation.
Olezarsen reduced postprandial triglyceride AUC by 55% and decreased intracellular lipid droplets in monocytes by 25.0% in hypertriglyceridemic patients.
A nationwide study assesses mortality risk and treatment effects in heart failure patients with pacemakers, suggesting key interventions.
Impella support during CHIP procedures in ILVD patients with severely impaired ventricular reserve reduces late major adverse events compared to standard interventions.
Finerenone reduced heart failure events and cardiovascular deaths in patients with heart failure and EF ≥40%, showing promise for HFpEF and HFmrEF treatments.
SGLT2i initiation within 6 weeks post-HF hospitalization reduced 1-year all-cause mortality by 25% (HR 0.75) compared to non-users in patients with newly diagnosed HFrEF.
The joint statement from major cardiology societies emphasizes the urgent need to address environmental risk factors in cardiovascular disease prevention.
In a 10-year-old girl, acute heart failure with LVEF of 17% was linked to a functional adrenal adenoma, which normalized after adrenalectomy.
Transfer patients with anticoagulation-associated intracerebral hemorrhage had longer times to anticoagulant reversal, but lower odds of in-hospital death (OR 0.78).
In group 1 pulmonary hypertension, 15% had elevated PAWP >15 mm Hg, yet demonstrated better left atrial function compared to those with combined pre- and postcapillary PH.