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RCT · n=17,604Expert CommentaryTrending on X
AUG 18PlutzkyCirculation
Semaglutide cuts hsCRP by ~38% and lowers MACE risk independent of weight loss and LDL.
Semaglutide may lower MACE in overweight patients with ASCVD without diabetes; leaves open long-term durability and broader applicability.
Guideline5 mentions
AUG 17BenjaminCirculation Population Health and Outcomes
2026 AHA/ACC Clinical Performance and Quality Measures for Patients With Atrial Fibrillation: A Report of the American College of Cardiology/American Heart Association Joint Committee on Performance Measures
These 5 measures enable standardized, equitable AF quality assessment; extends guidelines into actionable public reporting and pay-for-performance standards.
RCT · n=6,0015 mentionsTrending on X
AUG 14OstrominskiEuropean Journal of Heart Failure
Finerenone consistently improved clinical outcomes compared to placebo across all baseline hypertension categories (Pinteraction=0.32), including in the 12.9% of patients with apparent treatment-resistant hypertension.
Finerenone may improve BP and outcomes in aTRH; extends FINEARTS-HF findings to this subgroup but leaves dedicated trials open.
JL
meta-analysis · n=3,274
AUG 17RattkaJournal of Interventional Cardiac Electrophysiology
Combined CA and LAAC linked to ~56% higher arrhythmia recurrence versus CA alone.
One-stop CA+LAAC appears feasible in AF; leaves open whether combined use improves outcomes versus staged procedures.
cohort · n=1,1472 mentions
AUG 14EhrJACC Advances
Selective iliofemoral angiography after TF-TAVI shows similar vascular and access-site complications to routine angiography.
Selective angiography may suffice without excess major complications; leaves open whether routine use improves outcomes in randomized settings.
meta-analysis · n=10,1001 mentions
AUG 14BaeJournal of Clinical Medicine
CCTA-detected obstructive CAD is linked to ~618% higher perioperative MACE risk.
May enhance preoperative risk stratification with coronary CT; extends observational data but leaves open need for prospective validation.
cohort · n=6,4091 mentions
AUG 17MeibomEuropean Heart Journal - Valvular and Structural Heart Disease
Severe kidney impairment before TAVI is linked to ~207% higher one-year mortality versus eGFR ≥60.
Severe pre-TAVI kidney impairment signals high one-year mortality risk; leaves open whether renal optimization improves outcomes.
cohort · n=1,5383 mentionsTrending on XExpert Commentary
AUG 14OmoteJACC Advances
M-TEER in LVEF <20% does not increase 1-year death or HF hospitalization versus LVEF 20-40%.
Supports M-TEER feasibility in LVEF<20%; leaves open confirmation by randomized trials.
meta-analysis · n=77,5263 mentionsTrending on X
AUG 17RakabAging Clinical and Experimental Research
Short-term ECG screening increases new AF diagnoses ~76% but fails to reduce stroke or mortality.
Short-term ECG screening increases AF detection and OAC initiation without reducing stroke, mortality, or bleeding; leaves open the need for conclusive outcome trials.
systematic_review4 mentionsTrending on X
AUG 17AlrazeeniInternational Emergency Nursing
Artificial intelligence, particularly machine learning and deep learning approaches, enhances readmission risk prediction by effectively analyzing complex and multidimensional healthcare data.
Artificial intelligence models, particularly ensemble and neural networks, show strong potential to improve readmission risk prediction in emergency care, though external validation and system integration remain challenging.