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RCT · n=17,6046 mentionsExpert CommentaryTrending on X
AUG 18PlutzkyCirculation
Semaglutide cuts hsCRP by ~38% and lowers MACE risk independent of weight loss and LDL.
Semaglutide may lower MACE in overweight patients with ASCVD without diabetes; leaves open long-term durability and broader applicability.
Guideline5 mentions
AUG 17BenjaminCirculation Population Health and Outcomes
2026 AHA/ACC Clinical Performance and Quality Measures for Patients With Atrial Fibrillation: A Report of the American College of Cardiology/American Heart Association Joint Committee on Performance Measures
These 5 measures enable standardized, equitable AF quality assessment; extends guidelines into actionable public reporting and pay-for-performance standards.
RCT · n=6,0015 mentionsTrending on X
AUG 14OstrominskiEuropean Journal of Heart Failure
Finerenone consistently improved clinical outcomes compared to placebo across all baseline hypertension categories (Pinteraction=0.32), including in the 12.9% of patients with apparent treatment-resistant hypertension.
Finerenone may improve BP and outcomes in aTRH; extends FINEARTS-HF findings to this subgroup but leaves dedicated trials open.
JL
meta-analysis · n=3,2742 mentions
AUG 17RattkaJournal of Interventional Cardiac Electrophysiology
Combined CA and LAAC linked to ~56% higher arrhythmia recurrence versus CA alone.
One-stop CA+LAAC appears feasible in AF; leaves open whether combined use improves outcomes versus staged procedures.
cohort · n=1,1472 mentions
AUG 14EhrJACC Advances
Selective iliofemoral angiography after TF-TAVI shows similar vascular and access-site complications to routine angiography.
Selective angiography may suffice without excess major complications; leaves open whether routine use improves outcomes in randomized settings.
meta-analysis · n=10,1001 mentions
AUG 14BaeJournal of Clinical Medicine
CCTA-detected obstructive CAD is linked to ~618% higher perioperative MACE risk.
May enhance preoperative risk stratification with coronary CT; extends observational data but leaves open need for prospective validation.
meta-analysis · n=77,5266 mentionsTrending on X
AUG 17RakabAging Clinical and Experimental Research
Short-term ECG screening increases new AF diagnoses ~76% but fails to reduce stroke or mortality.
Short-term ECG screening increases AF detection and OAC initiation without reducing stroke, mortality, or bleeding; leaves open the need for conclusive outcome trials.
DEDr. Elsayed Balbaa
Cardiology, Ain Shams University
While short-term and intermittent ECG-based AF screening in older adults without known AF increased AF detection, it did not improve clinical outcomes, including stroke and mortality.
RCT · n=5121 mentions
AUG 17PassoCirculation Population Health and Outcomes
Multidomain cardiac rehabilitation cuts CV death or unplanned CV hospitalization ~43% in frail post-MI patients.
Supports multidomain cardiac rehabilitation in frail post-MI patients; extends evidence to this high-risk subgroup.
cohort · n=6,4091 mentions
AUG 17MeibomEuropean Heart Journal - Valvular and Structural Heart Disease
Severe kidney impairment before TAVI is linked to ~207% higher one-year mortality versus eGFR ≥60.
Severe pre-TAVI kidney impairment signals high one-year mortality risk; leaves open whether renal optimization improves outcomes.
cohort · n=1,5383 mentionsTrending on XExpert Commentary
AUG 14OmoteJACC Advances
M-TEER in LVEF <20% does not increase 1-year death or HF hospitalization versus LVEF 20-40%.
Supports M-TEER feasibility in LVEF<20%; leaves open confirmation by randomized trials.
