Supplementary Figure S3 from T-cell Dependency of Tumor Regressions and Complete Responses with RAS(ON) Multi-selective Inhibition in Preclinical Models of Pancreatic Ductal Adenocarcinoma | Synapse
August 4, 2025
Supplementary Figure S3 from T-cell Dependency of Tumor Regressions and Complete Responses with RAS(ON) Multi-selective Inhibition in Preclinical Models of Pancreatic Ductal Adenocarcinoma
Key Points
T-cell dependency plays a crucial role in tumor regressions and complete responses in pancreatic ductal adenocarcinoma.
The study highlights significant effects of ras(on) multi-selective inhibition on stroma and vasculature in PDAC tumors.
Preclinical models were utilized to assess how ras(on) influences tumor dynamics and immune interactions.
Understanding these mechanisms may advance therapeutic strategies for pancreatic ductal adenocarcinoma treatment.
Abstract
Supplementary Figure S3: Effects of RAS(ON) multi-selective inhibition on stroma and vasculature in implanted PDAC tumors