Supplementary Figure 8 from ERBB2/HER2 Alterations in ctDNA and Metachronous Tissues of Patients with Metastatic Urothelial Cancer

Key Points

• ERBB2 mutation dynamics were observed in ctDNA and tissues from patients with metastatic urothelial cancer, highlighting its significance.
• The study analyzed serial tissue and ctDNA samples to track the evolution of ERBB2 alterations over time in individual patients.
• Findings demonstrate the importance of monitoring mutation dynamics in ctDNA as it may reflect tumor behavior and treatment response.
• This research suggests that understanding ERBB2 dynamics can help improve therapeutic strategies for metastatic urothelial cancer.