Figure S2 from TGFβ Inhibition during Radiotherapy Enhances Immune Cell Infiltration and Decreases Metastases in Ewing Sarcoma

Key Points

• Inhibiting TGFβ decreases metastases in Ewing sarcoma, leading to a more effective immune response.
• TGFβ1 was identified as the main isoform expressed by immune cells in human Ewing tumors.
• Research shows that enhancing immune cell infiltration via TGFβ inhibition can improve treatment outcomes.
• Findings imply a need for further exploration of TGFβ-targeted therapies in Ewing sarcoma management.