Synthesis of Multisubstituted Pyranoindol‐1‐ones Using Iridium‐Catalyzed Intramolecular C─H Amination of 3‐Amino‐4‐phenyl‐2‐pyrones

Key Points

• The synthetic strategy successfully developed pyranoindol-1-ones, showcasing its efficacy.
• Using iridium as a catalyst, the method simplifies the creation of complex compounds with a focus on efficiency.
• The approach relies on C─H amination of 3-amino-4-phenyl-2-pyrones derived from diethyl 2-aminomalonate.
• Potential analogues of biologically active compounds were synthesized, indicating future applications in pharmaceuticals.