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Senna is a highly-producing Leguminosae herb known as a ringworm plant. Antioxidants protect the body against reactive oxygen species-induced oxidative damage, which is linked to cardiovascular disease and cancer. Naturally occurring plant antioxidants are being considered as preventive medicine. Escherichia coli, Staphylococcus aurteus, Enterococcus faecalis, and Bacillus subtilis were examined for Senna alata extract secondary metabolites, antioxidant, and antibacterial activity. The plant leaf was phytochemically examined for alkaloids, tannins, general glycosides, steroids, and terpenoids. A quantitative study of leaf extract secondary metabolites was done. Results showed that alkaloids, tannins, steroids, and terpenoids had concentrations of 8.5±2.0mg/100g, 12.5±1.0mg/100g, 17.0±2.0mg/100g, 11.5±3.0mg/100g, and 16.0±3.1mg/100g, respectively. The study discovered that increasing the quantities of leaf extract directly enhanced the scavenging action of DPPH (2, 2-diphenyl-1-1-picrylhydrazyl). The antioxidant activity of the leaf extract was inferior to that of ascorbic acid. The test organisms were susceptible to the plant extract due to the presence of zones of inhibition. At the lowest concentration, the Senna alata leaf extract combined with Ethanol exhibited the highest level of inhibition against Escherichia coli and Staphylococcus aureus. The findings of this study suggest that the chemical compounds found in Senna alata leaf extract will have potential applications in chemotherapy.
Banso et al. (Sun,) studied this question.
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