Mp74-12 Impact of Magnetic Resonance Imaging Scan and Image Acquisition Protocol in Detecting Clinically Significant Prostate Cancer at Biopsy: Results From the Promod Working Group

You have accessJournal of UrologyProstate Cancer: Detection 388 patients were male (87.4%) At first TURBT, patients with T1b disease had larger tumors (>3 cm: 55.4% vs. 36.6%, p=0.003) when compared with those with T1a. At RE-TURBT, residual HG BC was found in 23% of T1a and 14.5% of T1b (p=0.1), while pathological upstaging (≥T2) was shown in 1.3% with T1a vs. 6.6% with T1b (p=0.04). At a median follow-up of 40 months (interquartile range=17-72 months), recurrence-free survival was 39.7% for the T1a group and 38.8% for the T1b group. Progression was observed in 27 (11.2%) and 21 (18.1%) patients with T1a and T1b disease (p=0.07). Cancer-specific survival was 83% and 75%, while cystectomy was performed in 16.5% versus 19%, respectively. Overall, patients with T1b disease had worse survival curves when compared to those with T1a, albeit this reached statistical significance only for PFS (p=0.01). At multivariable analyses, an adequate BCG course was an independent predictor for all outcomes evaluated (all p3 cm tumor size, and older age) may improve risk stratification and guide overall management disease. Source of Funding: None © 2024 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 211Issue 5SMay 2024Page: e1197 Advertisement Copyright & Permissions© 2024 by American Urological Association Education and Research, Inc.Metrics Author Information Antonio Fanelli More articles by this author Marco Finati More articles by this author Ugo Giovanni Falagario More articles by this author Anna Lantz More articles by this author Ivan Jambor More articles by this author Luca Carmignani More articles by this author Emanuele Montanari More articles by this author Pierluigi Bove More articles by this author Paolo Gontero More articles by this author Alessandro Sciarra More articles by this author Carlo Trombetta More articles by this author Pierfrancesco Bassi More articles by this author Giuseppe Simone More articles by this author Vincenzo Mirone More articles by this author Alessandro Antonelli More articles by this author Luigi Schips More articles by this author Gian Maria Busetto More articles by this author Carlo Bettocchi More articles by this author Mattero Ferro More articles by this author Peter Bostrom More articles by this author Tobias Nordstrom More articles by this author Ottavio De Cobelli More articles by this author Luigi Cormio More articles by this author Giuseppe Carrieri More articles by this author Expand All Advertisement PDF downloadLoading ...