Mp19-07 Towards a Tailored Use of Psa Density to Decide When to Avoid Prostate Biopsy in Men With Pirads 3 Lesions According to the Location of the Index Lesion at Mp-Mri. Results of a Large, Multi-Institutional Series

You have accessJournal of UrologyProstate Cancer: Detection p=0.01). Age (OR: 1.05), PIRADS 4 (OR: 5.1) and 5 (OR: 11) and number of targeted cores (OR: 1.1) were also independent predictors of csPCa (all p<0.001). Figure 1 shows that in patients with PIRADS 3 lesions different PSAd cut off should be used according to the index lesion location, being <0.05 vs <0.13 for PZ vs TZ, with 10 vs 50% potentially avoided biopsies, missing only 7% of csPCa. Conversely, patients with PIRADS≥4 had a risk of csPCa higher than 15% regardless of their PSAd values and lesions location. CONCLUSIONS: PSAd can be used to identify PI-RADS 3 patients that might avoid prostate biopsy. Particularly, men with PI-RADS 3 PZ and TZ lesions should be counselled for avoiding a biopsy in case of PSAd <0.05 and <0.13, respectively. Differently, patients with PI-RADS ≥4 should always be referred for a TBx. Download PPT Source of Funding: None © 2024 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 211Issue 5SMay 2024Page: e313 Advertisement Copyright & Permissions© 2024 by American Urological Association Education and Research, Inc.Metrics Author Information Leonardo Quarta More articles by this author Armando Stabile More articles by this author Francesco Barletta More articles by this author Elio Mazzone More articles by this author Donato Cannoletta More articles by this author Francesco Pellegrino More articles by this author Gabriele Sorce More articles by this author Antony Pellegrino More articles by this author Vito Cucchiara More articles by this author Simone Scuderi More articles by this author Daniele Robesti More articles by this author Riccardo Leni More articles by this author Giorgio Gandaglia More articles by this author Marco Bianchi More articles by this author Francesco De Cobelli More articles by this author Giorgio Brembilla More articles by this author Roupret Morgan More articles by this author R. Jeffrey Karnes More articles by this author Francesco Montorsi More articles by this author Alberto Briganti More articles by this author Expand All Advertisement PDF downloadLoading ...