APOE ε4 does not appear to be a specific risk factor for white matter hyperintensities in American Indians, indicating a need for further research.
Does the APOE ε4 allele act as a specific risk factor for longitudinal vascular brain injury (WMH) in American Indians?
APOE ε4 does not appear to be a specific risk factor for white matter hyperintensities in American Indians, echoing previous findings.
Absolute Event Rate: 0% vs 0%
Our findings echo previous work that APOE e4 does not appear to have specificity as a risk factor WMH in American Indians. Further research in a larger sample size and as well as how modifiable environmental factors might modify the biological effects of APOE ε4 on brain aging in American Indians is required to validate these findings.
Hayes et al. (Tue,) reported a other. APOE ε4 does not appear to be a specific risk factor for white matter hyperintensities in American Indians, indicating a need for further research.