Liquid metal is considered an intelligent material capable of responding to environmental changes, and its applications in the biomedical field have been widely explored. In this work, we have developed a gallium-indium alloy nanomaterial (EGaIn-PEG NPs) as an intelligent platform for precise tumor photothermal therapy. Our research demonstrates that EGaIn-PEG NPs exhibit excellent computed tomography (CT) imaging contrast performance. Furthermore, under 1064 nm laser irradiation, EGaIn-PEG NPs show efficient heating effects, high photothermal conversion efficiency, and stability, enabling CT-guided tumor NIR-II photothermal therapy. This work promises to offer insights into the application of liquid metals for NIR-II tumor photothermal therapy.
Lin et al. (Thu,) studied this question.